DeepDigest: Prediction of Protein Proteolytic Digestion with Deep Learning.
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DOI: 10.1021/acs.analchem.0c04704
Abstract: Proteolytic digestion of proteins by one or more proteases is a key step in shotgun proteomics, in which the proteolytic products, i.e., peptides, are taken as the surrogates of their parent proteins for further qualitative… read more here.
Keywords: protein; cleavage; digestion; deep learning ... See more keywords
Characterization of Affitin proteolytic digestion in biorelevant media and improvement of their stabilities via protein engineering
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-76855-z
Abstract: Affitins are a novel class of small 7 kDa artificial proteins which can be used as antibody substitutes in therapeutic, diagnostic and biotechnological applications. One challenge for this type of protein agent is their behaviour… read more here.
Keywords: protein; biorelevant media; protein engineering; digestion ... See more keywords