Proteomic analysis of the secretome of HepG2 cells indicates differential proteolytic processing after infection with dengue virus.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of proteomics"
DOI: 10.1016/j.jprot.2016.07.011
Abstract: Secretome analysis can be described as a subset of proteomics studies consisting in the analysis of the molecules secreted by cells or tissues. Dengue virus (DENV) infection can lead to a broad spectrum of clinical… read more here.
Keywords: analysis; infection; hepg2 cells; proteolytic processing ... See more keywords
Topovectorial mechanisms control the juxtamembrane proteolytic processing of Nrf1 to remove its N‐terminal polypeptides during maturation of the CNC‐bZIP factor
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2018.09.039
Abstract: &NA; The topobiological behaviour of Nrf1 dictates its post‐translational modification and its ability to transactivate target genes. Here, we have elucidated that topovectorial mechanisms control the juxtamembrane processing of Nrf1 on the cyto/nucleoplasmic side of… read more here.
Keywords: topovectorial mechanisms; juxtamembrane; mechanisms control; proteolytic processing ... See more keywords
Proteolytic Processing of CD44 and Its Implications in Cancer
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DOI: 10.1155/2021/6667735
Abstract: CD44 is a transmembrane glycoprotein expressed in several healthy and tumor tissues. Modifications in its structure contribute differently to the activity of this molecule. One modification that has provoked interest is the consecutive cleavage of… read more here.
Keywords: processing cd44; cd44; proteolytic processing; cancer ... See more keywords
Characterization of the Proprotein Convertase-Mediated Processing of Peroxidasin and Peroxidasin-like Protein
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DOI: 10.3390/antiox10101565
Abstract: Peroxidasin (PXDN) and peroxidasin-like protein (PXDNL) are members of the peroxidase-cyclooxygenase superfamily. PXDN functions in basement membrane synthesis by forming collagen IV crosslinks, while the function of PXDNL remains practically unknown. In this work, we… read more here.
Keywords: peroxidasin like; proprotein convertase; like protein; peroxidasin ... See more keywords