Heparan Sulfated Glypican-4 Is Released from Astrocytes by Proteolytic Shedding and GPI-Anchor Cleavage Mechanisms
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DOI: 10.1523/eneuro.0069-21.2021
Abstract: Visual Abstract Astrocytes provide neurons with diffusible factors that promote synapse formation and maturation. In particular, glypican-4/GPC4 released from astrocytes promotes the maturation of excitatory synapses. Unlike other secreted factors, GPC4 contains the C-terminal GPI-anchorage… read more here.
Keywords: proteolytic shedding; gpi anchor; gpc4; release ... See more keywords