Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Sign Up to like & getrecommendations! Published in 2025 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13817
Abstract: Immune status critically affects cancer progression and therapy responses. This study aimed to identify plasma proteome changes in immunosuppressive cancer and potential biomarkers predicting systemic immunosuppression. Mouse models of syngeneic breast tumors (benign 67NR and… read more here.
Keywords: peripheral blood; cancer; cancer progression; proteome ... See more keywords
A comparison of prenatal muscle transcriptome and proteome profiles between pigs with divergent growth phenotypes
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27802
Abstract: The growth of pigs is an important economic trait that involves multiple genes and coordinated regulatory mechanisms. The growth rate and potential of skeletal muscles are largely decided by embryonic myofiber development. Tibetan pig (TP)… read more here.
Keywords: muscle; prenatal muscle; growth rate; growth ... See more keywords
Proteomic analysis of koala (phascolarctos cinereus) spermatozoa and prostatic bodies
Sign Up to like & getrecommendations! Published in 2021 at "PROTEOMICS"
DOI: 10.1002/pmic.202100067
Abstract: The aims of this study were to investigate the proteome of koala spermatozoa and that of the prostatic bodies with which they interact during ejaculation. For this purpose, spermatozoa and prostatic bodies were fractionated from… read more here.
Keywords: spermatozoa; spermatozoa prostatic; analysis; koala ... See more keywords
Blood proteome of acute intracranial hemorrhage in infant victims of abusive head trauma
Sign Up to like & getrecommendations! Published in 2022 at "PROTEOMICS"
DOI: 10.1002/pmic.202200078
Abstract: Abusive head trauma (AHT) is a leading cause of mortality and morbidity in infants. While the reported incidence is close to 40 cases per 100′000 births/year, misdiagnoses are commonly observed in cases with atypical, subacute,… read more here.
Keywords: blood; head trauma; proteome; abusive head ... See more keywords
Quantitative MS Workflow for a High-Quality Secretome Analysis by a Quantitative Secretome-Proteome Comparison.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1024-4_21
Abstract: Cells secrete proteins to communicate with their environment. Therefore, it is interesting to characterize the proteins which are released from cells under certain experimental conditions the so-called secretome. Here, often proteins from conditioned medium of… read more here.
Keywords: analysis; high quality; quality secretome; comparison ... See more keywords
Lab-on-a-Filter Techniques for Economical, Effective, and Flexible Proteome Analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1186-9_3
Abstract: Effective and reliable protease digestion of biological samples is critical to the success in bottom-up proteomics analysis. Various filter-based approaches using different types of membranes have been developed in the past several years and largely… read more here.
Keywords: filter techniques; techniques economical; lab filter; filter ... See more keywords
Differences in the cerebral amyloid angiopathy proteome in Alzheimer’s disease and mild cognitive impairment
Sign Up to like & getrecommendations! Published in 2024 at "Acta Neuropathologica"
DOI: 10.1007/s00401-024-02767-1
Abstract: Cerebral amyloid angiopathy (CAA) is characterized by amyloid beta (Aβ) deposition in cerebrovasculature. It is prevalent with aging and Alzheimer’s disease (AD), associated with intracerebral hemorrhage, and contributes to cognitive deficits. To better understand molecular… read more here.
Keywords: cerebral amyloid; caa vessels; amyloid angiopathy; proteome ... See more keywords
Proteome of exhaled breath condensate on exposure to high-temperature thermoheliox
Sign Up to like & getrecommendations! Published in 2020 at "Russian Chemical Bulletin"
DOI: 10.1007/s11172-020-2967-4
Abstract: The proteome of exhaled breath condensate was analyzed by mass spectrometry before and immediately after the thermoheliox procedure and after a 3 h relaxation. The major part of the proteome remained unchanged and there was… read more here.
Keywords: exhaled breath; breath condensate; proteome exhaled; proteome ... See more keywords
Pumilio2 and Staufen2 selectively balance the synaptic proteome.
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.109279
Abstract: Neurons have the capacity to adapt to environmental stimuli, a phenomenon termed cellular plasticity. The underlying processes are controlled by a network of RNA-binding proteins (RBPs). Their precise impact, however, is largely unknown. To address… read more here.
Keywords: staufen2 selectively; selectively balance; pumilio2 staufen2; balance synaptic ... See more keywords
Proteomic and metabolomic profiling of urine uncovers immune responses in patients with COVID-19
Sign Up to like & getrecommendations! Published in 2021 at "Cell Reports"
DOI: 10.1016/j.celrep.2021.110271
Abstract: The utility of the urinary proteome in infectious diseases remains unclear. Here we analyzed the proteome and metabolome of urine and serum samples from patients with COVID-19 and healthy controls. Our data show that urinary… read more here.
Keywords: metabolomic profiling; urinary proteome; profiling urine; proteomic metabolomic ... See more keywords
SARS-CoV-2 3CLpro whole human proteome cleavage prediction and enrichment/depletion analysis
Sign Up to like & getrecommendations! Published in 2022 at "Computational Biology and Chemistry"
DOI: 10.1016/j.compbiolchem.2022.107671
Abstract: A novel coronavirus (SARS-CoV-2) has devastated the globe as a pandemic that has killed millions of people. Widespread vaccination is still uncertain, so many scientific efforts have been directed toward discovering antiviral treatments. Many drugs… read more here.
Keywords: human proteome; sars cov; cleavage; cleavage prediction ... See more keywords