Rewiring of the ubiquitinated proteome determines ageing in C. elegans
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DOI: 10.1038/s41586-021-03781-z
Abstract: Ageing is driven by a loss of cellular integrity1. Given the major role of ubiquitin modifications in cell function2, here we assess the link between ubiquitination and ageing by quantifying whole-proteome ubiquitin signatures in Caenorhabditis… read more here.
Keywords: degradation; longevity; determines ageing; proteome determines ... See more keywords