Interactome and Proteome Dynamics Uncover Immune Modulatory Associations of the Pathogen Sensing Factor cGAS.
Sign Up to like & getrecommendations! Published in 2018 at "Cell systems"
DOI: 10.1016/j.cels.2018.10.010
Abstract: Viral DNA sensing is an essential component of the mammalian innate immune response. Upon binding viral DNA, the cyclic-GMP-AMP synthase (cGAS) catalyzes the production of cyclic dinucleotides to induce type I interferons. However, little is… read more here.
Keywords: dynamics uncover; cgas; interactome proteome; uncover immune ... See more keywords
Platelet proteome dynamics in hibernating 13-lined ground squirrels.
Sign Up to like & getrecommendations! Published in 2021 at "Physiological genomics"
DOI: 10.1152/physiolgenomics.00078.2021
Abstract: Hibernating mammals undergo a dramatic drop in temperature and blood flow during torpor, yet avoid stasis blood clotting through mechanisms that remain unspecified. The effects of hibernation on hemostasis are especially complex, as cold temperatures… read more here.
Keywords: proteome dynamics; ground; ground squirrels; cold storage ... See more keywords
Heterogeneity of proteome dynamics between connective tissue phases of adult tendon
Sign Up to like & getrecommendations! Published in 2020 at "eLife"
DOI: 10.7554/elife.55262
Abstract: Maintenance of connective tissue integrity is fundamental to sustain function, requiring protein turnover to repair damaged tissue. However, connective tissue proteome dynamics remain largely undefined, as do differences in turnover rates of individual proteins in… read more here.
Keywords: connective tissue; proteome dynamics; turnover rates; tissue ... See more keywords