Exploration of variations in proteome and metabolome for predictive diagnostics and personalized treatment algorithms: Innovative approach and examples for potential clinical application.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of proteomics"
DOI: 10.1016/j.jprot.2017.08.020
Abstract: Genome mutually interacts with internal and external environmental factors to result in different phenome that contains two important elements of proteins and metabolites, which link genome to predictive, preventive and personalized medicine (PPPM) or precision… read more here.
Keywords: medicine; variations proteome; exploration variations; proteome metabolome ... See more keywords
Responses of the Proteome and Metabolome in Livers of Zebrafish Exposed Chronically to Environmentally Relevant Concentrations of Microcystin-LR.
Sign Up to like & getrecommendations! Published in 2017 at "Environmental science & technology"
DOI: 10.1021/acs.est.6b03990
Abstract: In this study, for the first time, changes in expressions of proteins and profiles of metabolites in liver of the small, freshwater fish [Formula: see text] (zebrafish) were investigated after long-term exposure to environmentally relevant… read more here.
Keywords: concentrations microcystin; zebrafish exposed; responses proteome; proteome metabolome ... See more keywords
Impact of Left Ventricular Assist Device Therapy on the Cardiac Proteome and Metabolome Composition in Ischemic Cardiomyopathy.
Sign Up to like & getrecommendations! Published in 2019 at "Artificial organs"
DOI: 10.1111/aor.13566
Abstract: BACKGROUND The changes in the myocardial proteome and metabolome associated with left ventricular assist device (LVAD) therapy in patients with ischemic cardiomyopathy (ICM) are poorly characterized. We investigated the impact of mechanical unloading following LVAD… read more here.
Keywords: proteome metabolome; lvad therapy; biology; therapy ... See more keywords
Pre-analytical processing of plasma and serum samples for combined proteome and metabolome analysis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.961448
Abstract: Metabolomic and proteomic analyses of human plasma and serum samples harbour the power to advance our understanding of disease biology. Pre-analytical factors may contribute to variability and bias in the detection of analytes, especially when… read more here.
Keywords: proteome metabolome; pre analytical; plasma serum; serum samples ... See more keywords