Proteome and phosphoproteome profiling of non‐small cell lung cancer cell line A549 treated with TRAIL
Sign Up to like & getrecommendations! Published in 2022 at "PROTEOMICS"
DOI: 10.1002/pmic.202200248
Abstract: Tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL) is recognized for its promising therapeutic effects against cancer. However, mechanisms underlying the effect of TRAIL on protein expression, signal transduction, and apoptosis induction remain unclear. We surmised that… read more here.
Keywords: trail; cell; non small; small cell ... See more keywords
Abstract 5498: SHP2 inhibition enhances antitumor effect of mirdametinib in a pediatric brain tumor model bearing CDC42SE2BRAF fusion by rewiring the proteome and phosphoproteome landscape
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-5498
Abstract: Pediatric gliomas are the most common type of pediatric brain tumors representing wide range of molecularly and clinically heterogenous subtypes. The hyperactivity of mitogen-activated protein kinases (MAPK) pathway has been identified in the majority of… read more here.
Keywords: mirdametinib; combination; brain; proteome phosphoproteome ... See more keywords
Alterations in the Proteome and Phosphoproteome Profiles of Rat Hippocampus after Six Months of Morphine Withdrawal: Comparison with the Forebrain Cortex
Sign Up to like & getrecommendations! Published in 2021 at "Biomedicines"
DOI: 10.3390/biomedicines10010080
Abstract: The knowledge about proteome changes proceeding during protracted opioid withdrawal is lacking. Therefore, the aim of this work was to analyze the spectrum of altered proteins in the rat hippocampus in comparison with the forebrain… read more here.
Keywords: rat hippocampus; morphine withdrawal; forebrain cortex; withdrawal ... See more keywords
Proteome and Phosphoproteome Changes Associated with Prognosis in Acute Myeloid Leukemia
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DOI: 10.3390/cancers12030709
Abstract: Acute myeloid leukemia (AML) is a hematological cancer that mainly affects the elderly. Although complete remission (CR) is achieved for the majority of the patients after induction and consolidation therapies, nearly two-thirds relapse within a… read more here.
Keywords: relapse; myeloid leukemia; proteome phosphoproteome; acute myeloid ... See more keywords
Integrative Proteome and Phosphoproteome Profiling of Early Cold Response in Maize Seedlings
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23126493
Abstract: Cold limits the growth and yield of maize in temperate regions, but the molecular mechanism of cold adaptation remains largely unexplored in maize. To identify early molecular events during cold shock, maize seedlings were treated… read more here.
Keywords: proteome phosphoproteome; response; maize seedlings; cold responsive ... See more keywords
Clostridiumnovyi’s Alpha-Toxin Changes Proteome and Phosphoproteome of HEp-2 Cells
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23179939
Abstract: C. novyi type A produces the alpha-toxin (TcnA) that belongs to the large clostridial glucosylating toxins (LCGTs) and is able to modify small GTPases by N-acetylglucosamination on conserved threonine residues. In contrast, other LCGTs including… read more here.
Keywords: tcna; alpha toxin; toxin; proteome phosphoproteome ... See more keywords