Articles with "proteomic approaches" as a keyword



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Proteomic Approaches to Dissect Neuronal Signalling Pathways.

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Published in 2019 at "Advances in experimental medicine and biology"

DOI: 10.1007/978-3-030-15950-4_27

Abstract: With an increasing awareness of mental health issues and neurological disorders, "understanding the brain" is one of the biggest current challenges in biological research. This has been recognised by both governments and funding agencies, and… read more here.

Keywords: dissect neuronal; signalling pathways; neuronal signalling; proteomic approaches ... See more keywords
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Proteomic approaches beyond expression profiling and PTM analysis

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Published in 2018 at "Analytical and Bioanalytical Chemistry"

DOI: 10.1007/s00216-018-1021-y

Abstract: Essentially, all cellular functions are executed by proteins. Different physiological and pathological conditions dynamically control various properties of proteins, including expression levels, post-translational modifications (PTMs), protein–protein interactions, enzymatic activity, etc. Thus far, the vast majority… read more here.

Keywords: protein; beyond expression; approaches beyond; analysis ... See more keywords
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Targeted Proteomic Approaches for Proteome-Wide Characterizations of the AMP-Binding Capacities of Kinases.

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Published in 2022 at "Journal of proteome research"

DOI: 10.1021/acs.jproteome.2c00225

Abstract: Kinases play important roles in cell signaling, and adenosine monophosphate (AMP) is known to modulate cellular energy homeostasis through AMP-activated protein kinase (AMPK). Here, we explored novel AMP-binding kinases by employing a desthiobiotin-conjugated AMP acyl-phosphate… read more here.

Keywords: binding capacities; amp binding; amp; targeted proteomic ... See more keywords
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Different chemical proteomic approaches to identify the targets of lapatinib

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Published in 2023 at "Journal of Enzyme Inhibition and Medicinal Chemistry"

DOI: 10.1080/14756366.2023.2183809

Abstract: Abstract The process of identifying the protein targets and off-targets of a biologically active compound is of great importance in modern drug discovery. Various chemical proteomics approaches have been established for this purpose. To compare… read more here.

Keywords: different chemical; identify targets; chemical proteomic; chemistry ... See more keywords
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Proteomic approaches to identify blood-based biomarkers for depression and bipolar disorders

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Published in 2018 at "Expert Review of Proteomics"

DOI: 10.1080/14789450.2018.1444483

Abstract: ABSTRACT Introduction: Major depressive disorder (MDD) and bipolar disorder (BD) are leading causes of disability worldwide, yet many people remain undiagnosed, are misdiagnosed, and/or ineffectively treated. Diagnosis relies on the clinical assessment of symptoms, and… read more here.

Keywords: approaches identify; identify blood; proteomic approaches; blood ... See more keywords
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Revealing the Amylase Interactome in Whole Saliva Using Proteomic Approaches

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Published in 2018 at "BioMed Research International"

DOI: 10.1155/2018/6346954

Abstract: Understanding proteins present in saliva and their function when isolated is not enough to describe their real role in the mouth. Due to protein-protein interactions, structural changes may occur in macromolecules leading to functional modulation… read more here.

Keywords: using proteomic; saliva; whole saliva; amylase ... See more keywords
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Proteomic Approaches to Unravel Mechanisms of Antibiotic Resistance and Immune Evasion of Bacterial Pathogens

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Published in 2022 at "Frontiers in Medicine"

DOI: 10.3389/fmed.2022.850374

Abstract: The profound effects of and distress caused by the global COVID-19 pandemic highlighted what has been known in the health sciences a long time ago: that bacteria, fungi, viruses, and parasites continue to present a… read more here.

Keywords: antibiotic resistance; unravel mechanisms; proteomic approaches; resistance ... See more keywords
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Editorial: Proteomic Approaches to Unravel Mechanisms of Resistance and Immune Evasion of Bacterial Pathogens

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Published in 2022 at "Frontiers in Medicine"

DOI: 10.3389/fmed.2022.945264

Abstract: Clinical Microbiology Lab, University Hospital Marqués de Valdecilla, Santander, Spain, 2 Instituto de Investigación Sanitaria Marqués de Valdecilla (IDIVAL), Santander, Spain, 3 Sharjah Institute of Medical Research, University of Sharjah, Sharjah, United Arab Emirates, Department… read more here.

Keywords: editorial proteomic; university; unravel mechanisms; proteomic approaches ... See more keywords
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Proteomic Approaches to Dissect Host SUMOylation during Innate Antiviral Immune Responses

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Published in 2021 at "Viruses"

DOI: 10.3390/v13030528

Abstract: SUMOylation is a highly dynamic ubiquitin-like post-translational modification that is essential for cells to respond to and resolve various genotoxic and proteotoxic stresses. Virus infections also constitute a considerable stress scenario for cells, and recent… read more here.

Keywords: sumoylation; sumoylation innate; proteomic approaches; host ... See more keywords