Proteomic mapping of Drosophila transgenic elav.L-GAL4/+ brain as a tool to illuminate neuropathology mechanisms
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-62510-0
Abstract: Drosophila brain has emerged as a powerful model system for the investigation of genes being related to neurological pathologies. To map the proteomic landscape of fly brain, in a high-resolution scale, we herein employed a… read more here.
Keywords: drosophila; gal4; mapping drosophila; elav ... See more keywords
Proteomic mapping and optogenetic manipulation of membrane contact sites
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DOI: 10.1042/bcj20220382
Abstract: Membrane contact sites (MCSs) mediate crucial physiological processes in eukaryotic cells, including ion signaling, lipid metabolism, and autophagy. Dysregulation of MCSs is closely related to various diseases, such as type 2 diabetes mellitus (T2DM), neurodegenerative… read more here.
Keywords: mapping; contact sites; membrane contact; proteomic mapping ... See more keywords
Proteomic mapping and targeting of mitotic pericentriolar material in tumors bearing centrosome amplification.
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DOI: 10.1158/0008-5472.can-22-0225
Abstract: Recent work has made it clear that pericentriolar material (PCM), the matrix of proteins surrounding centrioles, contributes to most functions of centrosomes. Given the occurrence of centrosome amplification in most solid tumors and the unconventional… read more here.
Keywords: pericentriolar material; centrosome amplification; pcm; proteomic mapping ... See more keywords