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Published in 2022 at "Current Treatment Options in Oncology"
DOI: 10.1007/s11864-022-00947-3
Abstract: Advances in proteomic and metabolomic technologies have accelerated our understanding of multiple aspects of cancer biology across distinct tumour types. Here we review the current state-of-the-art in the use of proteomics and metabolomics in soft…
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Keywords:
tissue sarcomas;
proteomic metabolomic;
metabolomic profiling;
soft tissue ... See more keywords
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Published in 2020 at "Cell"
DOI: 10.1016/j.cell.2020.05.032
Abstract: Summary Early detection and effective treatment of severe COVID-19 patients remain major challenges. Here, we performed proteomic and metabolomic profiling of sera from 46 COVID-19 and 53 control individuals. We then trained a machine learning…
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Keywords:
covid patients;
metabolomic characterization;
proteomic metabolomic;
characterization covid ... See more keywords
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Published in 2017 at "Cell reports"
DOI: 10.1016/j.celrep.2017.06.074
Abstract: There exist similarities and differences in metabolism and physiology between normal proliferative cells and tumor cells. Once a cell enters the cell cycle, metabolic machinery is engaged to facilitate various processes. The kinetics and regulation…
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Keywords:
transition;
proteomic metabolomic;
proliferation;
quiescence proliferation ... See more keywords
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Published in 2021 at "Cell Reports"
DOI: 10.1016/j.celrep.2021.110271
Abstract: The utility of the urinary proteome in infectious diseases remains unclear. Here we analyzed the proteome and metabolome of urine and serum samples from patients with COVID-19 and healthy controls. Our data show that urinary…
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Keywords:
metabolomic profiling;
urinary proteome;
profiling urine;
proteomic metabolomic ... See more keywords
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Published in 2019 at "Phytopathology"
DOI: 10.1094/phyto-03-19-0083-r
Abstract: Xylella fastidiosa releases outer membrane vesicles (OMVs) known to play a role in the systemic dissemination of this pathogen. OMVs inhibit bacterial attachment to xylem wall and traffic lipases/esterases that act on the degradation of…
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Keywords:
omv enriched;
proteomic metabolomic;
xylella fastidiosa;
family ... See more keywords
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Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abo6764
Abstract: Alzheimer’s disease (AD) is a heterogeneous disorder with abnormalities in multiple biological domains. In an advanced machine learning analysis of postmortem brain and in vivo blood multi-omics molecular data (N = 1863), we integrated epigenomic,…
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Keywords:
epigenomic transcriptomic;
alzheimer disease;
proteomic metabolomic;
taxonomy ... See more keywords
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Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.954121
Abstract: Although tremendous effort has been exerted to elucidate the pathogenesis of severe COVID-19 cases, the detailed mechanism of moderate cases, which accounts for 90% of all patients, remains unclear yet, partly limited by lacking the…
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Keywords:
proteomic metabolomic;
cynomolgus;
characterization sars;
stage ... See more keywords
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Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.894533
Abstract: Phytophthora cinnamomi Rands is a cosmopolite pathogen of woody plants which during the last couple of centuries has spread all over the world from its center of origin in Southeast Asia. In contrast to Chinese…
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Keywords:
quercus variabilis;
quercus suber;
proteomic metabolomic;
phytophthora cinnamomi ... See more keywords
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Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2021.792227
Abstract: Proteomics and metabolomics are two emerging fields that hold promise to shine light on the molecular mechanisms causing neurodegenerative diseases. Research in this area may reveal and quantify specific metabolites and proteins that can be…
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Keywords:
proteomic metabolomic;
metabolomic profiling;
advances proteomic;
neurodegenerative diseases ... See more keywords
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Published in 2022 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2022.1013328
Abstract: Migraine is a neurovascular disease with a high disability rate. Acupuncture treatment has emerged as a safe and viable alternative prophylactic therapy that can effectively alleviate the duration and frequency of migraine attacks. However, the…
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Keywords:
acupuncture;
proteomic metabolomic;
migraine;
metabolomic profiling ... See more keywords
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Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.958312
Abstract: Peaches and nectarines are temperate climate stone fruits, which should be stored at 0°C to prevent the ripening of these climacteric fruits. However, if stored for too long or if stored at a higher temperature…
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Keywords:
chilling injury;
proteomic metabolomic;
metabolomic studies;
injury peach ... See more keywords