Applications of proteomic methods for CHO host cell protein characterization in biopharmaceutical manufacturing.
Sign Up to like & getrecommendations! Published in 2018 at "Current opinion in biotechnology"
DOI: 10.1016/j.copbio.2018.01.004
Abstract: Chinese hamster ovary (CHO) cells are the most prevalent host organism for production of recombinant therapeutic proteins, including monoclonal antibodies (mAbs). Regulatory guidance mandates control of the host cell protein (HCP) concentration in the production… read more here.
Keywords: applications proteomic; host cell; cell protein; host ... See more keywords
An overview of proteomic methods for the study of ‘cytokine storms’
Sign Up to like & getrecommendations! Published in 2021 at "Expert Review of Proteomics"
DOI: 10.1080/14789450.2021.1911652
Abstract: ABSTRACT Introduction: The cytokine storm is a form of excessive systemic inflammatory reaction triggered by a myriad of factors that may lead to multi-organ failure, and finally to death. The cytokine storm can occur in… read more here.
Keywords: cytokine; methods study; cytokine storm; overview proteomic ... See more keywords