Proteomic and phosphoproteomic landscape of salivary extracellular vesicles to assess OSCC therapeutical outcomes
Sign Up to like & getrecommendations! Published in 2022 at "PROTEOMICS"
DOI: 10.1002/pmic.202200319
Abstract: Circulating extracellular vesicles (EVs) have emerged as an appealing source for surrogates to evaluate the disease status. Herein, we present a novel proteomic strategy to identify proteins and phosphoproteins from salivary EVs to distinguish oral… read more here.
Keywords: landscape salivary; therapeutical outcomes; extracellular vesicles; phosphoproteomic landscape ... See more keywords
Quantitative proteomic and phosphoproteomic studies reveal novel 5-fluorouracil resistant targets in hepatocellular carcinoma.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of proteomics"
DOI: 10.1016/j.jprot.2019.103501
Abstract: The development of chemoresistance remains the major obstacles to successful chemotherapy of hepatocellular carcinoma. The molecular mechanisms of drug resistance are complex. Identifying the key markers is crucial for development of therapeutic strategies to overcome… read more here.
Keywords: hepatocellular carcinoma; cell line; proteomic phosphoproteomic; resistance ... See more keywords
Temporal Proteomic and Phosphoproteomic Analysis of EV-A71-Infected Human Cells.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.2c00237
Abstract: Human enterovirus A71 (EV-A71), a member of the Picornaviridae family, is one of the main etiological viruses that lead to hand, foot, and mouth disease (HFMD). We utilized a multiplex tandem mass tag-based quantitative proteomic… read more here.
Keywords: phosphoproteomic analysis; analysis a71; a71; temporal proteomic ... See more keywords
Proteomic and Phosphoproteomic Analyses Reveal Gibel Carp Responses to Cyprinid Herpesvirus 2 Infection.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.2c00253
Abstract: Cyprinid herpesvirus 2 (CyHV-2) is a typical linear double-stranded DNA virus, which can induce severe herpesviral hematopoietic necrosis disease (HVHND) in gibel carp. However, the CyHV-2 infection mechanisms still remain unresolved till now. Here, we… read more here.
Keywords: proteomic phosphoproteomic; infection; gibel carp; host ... See more keywords
Integrative Proteomic and Phosphoproteomic Analyses Revealed the Regulatory Mechanism of the Response to Ultraviolet B Stress in Clematis ternifloraDC
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c07258
Abstract: Clematis ternifloraDC. (C. terniflora) has been used as an ancient Chinese traditional herbal medicine. The active substances in C. terniflora have been confirmed to be effective in treating diseases such as prostatitis. UV light radiation… read more here.
Keywords: phosphoproteomic analyses; stress; proteomic phosphoproteomic; clematis ternifloradc ... See more keywords
Proteomics and phosphoproteomics of failing human left ventricle identifies dilated cardiomyopathy-associated phosphorylation of CTNNA3.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2212118120
Abstract: The prognosis and treatment outcomes of heart failure (HF) patients rely heavily on disease etiology, yet the majority of underlying signaling mechanisms are complex and not fully elucidated. Phosphorylation is a major point of protein… read more here.
Keywords: left ventricle; etiology; ctnna3; phosphorylation ... See more keywords
Proteomic and phosphoproteomic landscapes of acute myeloid leukemia
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DOI: 10.1182/blood.2022016033
Abstract: Key Points A deep-scale proteomic and phosphoproteomic database of AML was produced and can be explored interactively (www.leylab.org/amlproteome). Posttranscriptionally regulated proteins were identified globally and associated with specific AML-initiating events. read more here.
Keywords: myeloid leukemia; landscapes acute; acute myeloid; phosphoproteomic landscapes ... See more keywords
Integrative Proteomic and Phosphoproteomic Analyses of Granulosa Cells During Follicular Atresia in Porcine
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.624985
Abstract: Ovarian follicular atresia is a natural physiological process; however, the mechanism is not fully understood. In this study, quantitative proteomic and phosphoproteomic analyses of granulosa cells (GCs) in healthy (H), slightly atretic (SA), and atretic… read more here.
Keywords: granulosa cells; analyses granulosa; follicular atresia; caspase6 ... See more keywords
Bioinformatics Analysis of Global Proteomic and Phosphoproteomic Data Sets Revealed Activation of NEK2 and AURKA in Cancers
Sign Up to like & getrecommendations! Published in 2020 at "Biomolecules"
DOI: 10.3390/biom10020237
Abstract: Tumor heterogeneity attributes substantial challenges in determining the treatment regimen. Along with the conventional treatment, such as chemotherapy and radiotherapy, targeted therapy has greater impact in cancer management. Owing to the recent advancements in proteomics,… read more here.
Keywords: data sets; analysis; proteomic phosphoproteomic; aurka ... See more keywords