POSREG: proteomic signature discovered by simultaneously optimizing its reproducibility and generalizability
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in bioinformatics"
DOI: 10.1093/bib/bbac040
Abstract: Mass spectrometry-based proteomic technique has become indispensable in current exploration of complex and dynamic biological processes. Instrument development has largely ensured the effective production of proteomic data, which necessitates commensurate advances in statistical framework to… read more here.
Keywords: proteomic signature; simultaneously optimizing; optimizing reproducibility; signature ... See more keywords
Plasma proteomic signature of age in healthy humans
Sign Up to like & getrecommendations! Published in 2018 at "Aging Cell"
DOI: 10.1111/acel.12799
Abstract: To characterize the proteomic signature of chronological age, 1,301 proteins were measured in plasma using the SOMAscan assay (SomaLogic, Boulder, CO, USA) in a population of 240 healthy men and women, 22–93 years old, who… read more here.
Keywords: age healthy; plasma proteomic; age; signature age ... See more keywords
OP0312 A proteomic signature of fatigue in primary sjÖgren's syndrome
Sign Up to like & getrecommendations! Published in 2017 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2017-eular.3973
Abstract: Background Fatigue is a frequent and often disabling phenomenon in patients with chronic inflammatory and immunological diseases, neurodegenerative diseases, and cancer. The underlying biological mechanisms of fatigue are largely unknown and hypotheses are conflicting. It… read more here.
Keywords: gren syndrome; proteomic signature; fatigue; primary gren ... See more keywords
The circulating proteomic signature of alcohol-associated liver disease
Sign Up to like & getrecommendations! Published in 2022 at "JCI Insight"
DOI: 10.1172/jci.insight.159775
Abstract: Despite being a leading cause of advanced liver disease, alcohol-associated liver disease (ALD) has no effective medical therapies. The circulating proteome, which comprises proteins secreted by different cells and tissues in the context of normal… read more here.
Keywords: proteomic signature; circulating proteomic; associated liver; disease ... See more keywords
Comprehensive proteomic signature and identification of CDKN2A as a promising prognostic biomarker and therapeutic target of colorectal cancer
Sign Up to like & getrecommendations! Published in 2022 at "World Journal of Clinical Cases"
DOI: 10.12998/wjcc.v10.i22.7686
Abstract: BACKGROUND The carcinogenesis of colorectal cancer (CRC) involves many different molecules and multiple pathways, and the specific mechanism has not been elucidated until now. Existing studies on the proteomic signature profiles of CRC are relatively… read more here.
Keywords: proteomic signature; signature; analysis; cdkn2a ... See more keywords
A Novel Blood Proteomic Signature for Prostate Cancer
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15041051
Abstract: Simple Summary Despite intensive research, effective tools for detection and monitoring of prostate cancer remain to be found. Prostate-specific antigen (PSA), commonly used in prostate cancer assessments, can lead to overdiagnosis and overtreatment of indolent… read more here.
Keywords: proteomic signature; signature prostate; prostate cancer; cancer ... See more keywords
Proteomic Signature and mRNA Expression in Hippocampus of SAMP8 and SAMR1 Mice during Aging
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232315097
Abstract: Aging is a complex process often accompanied by cognitive decline that represents a risk factor for many neurodegenerative disorders including Alzheimer’s and Parkinson’s disease. The molecular mechanisms involved in age-related cognitive decline are not yet… read more here.
Keywords: proteomic signature; hippocampus samp8; inflammatory cytokines; expression ... See more keywords
Proteomic Signature of Extracellular Vesicles Associated with Colorectal Cancer
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28104227
Abstract: The proteins of extracellular vesicles (EVs) provide proteomic signatures that reflect molecular features of EV-producing cells, including cancer cells. Detection of cancer cell EV proteins is of great interest due to the development of novel… read more here.
Keywords: proteomic signature; vesicles associated; extracellular vesicles; colorectal cancer ... See more keywords
Proteomic profiling reveals a signature for optimizing prognostic prediction in Colon Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cancer"
DOI: 10.7150/jca.50630
Abstract: Previous studies developed prognostic signatures largely depended on transcriptome profiles. The purpose of our present study was to develop a proteomic signature to optimize the evaluation of prognosis of colon cancer patients. The proteomic data… read more here.
Keywords: cancer; cancer proteomic; proteomic signature; colon cancer ... See more keywords