Identification of proteomic signatures associated with COPD frequent exacerbators.
Sign Up to like & getrecommendations! Published in 2019 at "Life sciences"
DOI: 10.1016/j.lfs.2019.05.047
Abstract: AIMS Acute exacerbation is a major event that alters the natural course of chronic obstructive pulmonary disease (COPD), and recurrent exacerbation results in worse clinical outcomes and greater economic consequences. While some patients suffer frequent… read more here.
Keywords: identification proteomic; frequent exacerbations; proteomic signatures; copd frequent ... See more keywords
Transcriptomic and proteomic signatures of stemness and differentiation in the colon crypt
Sign Up to like & getrecommendations! Published in 2020 at "Communications Biology"
DOI: 10.1038/s42003-020-01181-z
Abstract: Intestinal stem cells are non-quiescent, dividing epithelial cells that rapidly differentiate into progenitor cells of the absorptive and secretory cell lineages. The kinetics of this process is rapid such that the epithelium is replaced weekly.… read more here.
Keywords: cell; proteomic signatures; colon; transcriptomic proteomic ... See more keywords
Unsupervised clustering to differentiate rheumatoid arthritis patients based on proteomic signatures.
Sign Up to like & getrecommendations! Published in 2023 at "Scandinavian journal of rheumatology"
DOI: 10.1080/03009742.2023.2196781
Abstract: OBJECTIVE Patients with rheumatoid arthritis (RA) have different presentations and prognoses. Cluster analysis based on proteomic signatures creates independent phenogroups of patients with different pathophysiological backgrounds. We aimed to identify distinct pathophysiological clusters of RA… read more here.
Keywords: proteomic signatures; unsupervised clustering; patients based; rheumatoid arthritis ... See more keywords
Proteomic Signatures of Epigenetic Age in African Green Monkey Cerebrospinal Fluid and Plasma
Sign Up to like & getrecommendations! Published in 2025 at "Aging Cell"
DOI: 10.1111/acel.70168
Abstract: Strategies to slow the aging process or mitigate its consequences on health rely on the validation of minimally‐invasive biomarkers of aging that can be used to track aging and test the effectiveness of antiaging interventions.… read more here.
Keywords: epigenetic age; african green; csf plasma; proteomic signatures ... See more keywords
Immune response and barrier dysfunction-related proteomic signatures in preclinical phase of Crohn’s disease highlight earliest events of pathogenesis
Sign Up to like & getrecommendations! Published in 2023 at "Gut"
DOI: 10.1136/gutjnl-2022-328421
Abstract: Objective The measure of serum proteome in the preclinical state of Crohn’s disease (CD) may provide insight into biological pathways involved in CD pathogenesis. We aimed to assess associations of serum proteins with future CD… read more here.
Keywords: proteomic signatures; barrier dysfunction; crohn disease; risk ... See more keywords
Abstract 3306: Comprehensive plasma profiling in NSCLC patients undergoing IO- and chemotherapy identifies potential proteomic signatures for progression-free survival
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.am2025-3306
Abstract: In NSCLC, the identification of circulating predictive biomarkers is critical to improve patient selection. Circulating biomarkers have the advantage of accessibility of samples but challenges arise in detecting disease-relevant biomarkers in plasma, where low-abundance circulating… read more here.
Keywords: progression free; free survival; proteomic signatures; plasma ... See more keywords
Abstract LB326: Inflammatory proteomic signatures of metabolically unhealthy obesity in association with colorectal cancer and adenoma
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.am2025-lb326
Abstract: Metabolically unhealthy obesity (MUO), marked by high visceral adiposity and unhealthy glycemic traits, is a risk factor for colorectal cancer (CRC) and adenoma (CRA). However, the underlying mechanisms of MUO are not fully understood. We… read more here.
Keywords: cancer; cra; unhealthy obesity; crc ... See more keywords
Abstract MP33: Inflammatory proteomic signatures of metabolically unhealthy obesity
Sign Up to like & getrecommendations! Published in 2025 at "Circulation"
DOI: 10.1161/cir.151.suppl_1.mp33
Abstract: Background: Obesity is a risk factor for CVD incidence and mortality. Accumulating evidence implicates viscerally located adiposity may be particularly relevant for the progression of cardiovascular risk factors, with chronic inflammation as a plausible causal… read more here.
Keywords: unhealthy obesity; obesity; inflammatory proteomic; risk ... See more keywords
Mapping proteomic signatures in iPSC-derived neutrophils: Modeling neutropenia
Sign Up to like & getrecommendations! Published in 2025 at "Blood"
DOI: 10.1182/blood-2025-1212
Abstract: Severe congenital neutropenia (SCN) encompasses a diverse range of genetic defects that impair the differentiation and function of neutrophil granulocytes. Our study aims to characterize proteomic differences in distinct developmental stages of neutrophils with pathogenic… read more here.
Keywords: differentiation; maturation stages; mapping proteomic; derived neutrophils ... See more keywords
Proteomic Signatures of Monocytes in Hereditary Recurrent Fevers
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.921253
Abstract: Hereditary periodic recurrent fevers (HRF) are monogenic autoinflammatory associated to mutations of some genes, such as diseases caused by mutations of including MEFV, TNFRSF1A and MVK genes. Despite the identification of the causative genes, the… read more here.
Keywords: proteomic signatures; monocytes hrf; recurrent fevers; analysis ... See more keywords
Proteomic signatures of infiltrative gastric cancer by proteomic and bioinformatic analysis
Sign Up to like & getrecommendations! Published in 2022 at "World Journal of Gastrointestinal Oncology"
DOI: 10.4251/wjgo.v14.i11.2097
Abstract: BACKGROUND Proteomic signatures of Ming's infiltrative gastric cancer (IGC) remain unknown. AIM To elucidate the molecular characteristics of IGC at the proteomics level. METHODS Twelve pairs of IGC and adjacent normal tissues were collected and… read more here.
Keywords: proteomic signatures; regulated proteins; gastric cancer; infiltrative gastric ... See more keywords