Identification of proteomic signatures associated with COPD frequent exacerbators.
Sign Up to like & getrecommendations! Published in 2019 at "Life sciences"
DOI: 10.1016/j.lfs.2019.05.047
Abstract: AIMS Acute exacerbation is a major event that alters the natural course of chronic obstructive pulmonary disease (COPD), and recurrent exacerbation results in worse clinical outcomes and greater economic consequences. While some patients suffer frequent… read more here.
Keywords: identification proteomic; frequent exacerbations; proteomic signatures; copd frequent ... See more keywords
Transcriptomic and proteomic signatures of stemness and differentiation in the colon crypt
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DOI: 10.1038/s42003-020-01181-z
Abstract: Intestinal stem cells are non-quiescent, dividing epithelial cells that rapidly differentiate into progenitor cells of the absorptive and secretory cell lineages. The kinetics of this process is rapid such that the epithelium is replaced weekly.… read more here.
Keywords: cell; proteomic signatures; colon; transcriptomic proteomic ... See more keywords
Unsupervised clustering to differentiate rheumatoid arthritis patients based on proteomic signatures.
Sign Up to like & getrecommendations! Published in 2023 at "Scandinavian journal of rheumatology"
DOI: 10.1080/03009742.2023.2196781
Abstract: OBJECTIVE Patients with rheumatoid arthritis (RA) have different presentations and prognoses. Cluster analysis based on proteomic signatures creates independent phenogroups of patients with different pathophysiological backgrounds. We aimed to identify distinct pathophysiological clusters of RA… read more here.
Keywords: proteomic signatures; unsupervised clustering; patients based; rheumatoid arthritis ... See more keywords
Immune response and barrier dysfunction-related proteomic signatures in preclinical phase of Crohn’s disease highlight earliest events of pathogenesis
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DOI: 10.1136/gutjnl-2022-328421
Abstract: Objective The measure of serum proteome in the preclinical state of Crohn’s disease (CD) may provide insight into biological pathways involved in CD pathogenesis. We aimed to assess associations of serum proteins with future CD… read more here.
Keywords: proteomic signatures; barrier dysfunction; crohn disease; risk ... See more keywords
Proteomic Signatures of Monocytes in Hereditary Recurrent Fevers
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DOI: 10.3389/fimmu.2022.921253
Abstract: Hereditary periodic recurrent fevers (HRF) are monogenic autoinflammatory associated to mutations of some genes, such as diseases caused by mutations of including MEFV, TNFRSF1A and MVK genes. Despite the identification of the causative genes, the… read more here.
Keywords: proteomic signatures; monocytes hrf; recurrent fevers; analysis ... See more keywords
Proteomic signatures of infiltrative gastric cancer by proteomic and bioinformatic analysis
Sign Up to like & getrecommendations! Published in 2022 at "World Journal of Gastrointestinal Oncology"
DOI: 10.4251/wjgo.v14.i11.2097
Abstract: BACKGROUND Proteomic signatures of Ming's infiltrative gastric cancer (IGC) remain unknown. AIM To elucidate the molecular characteristics of IGC at the proteomics level. METHODS Twelve pairs of IGC and adjacent normal tissues were collected and… read more here.
Keywords: proteomic signatures; regulated proteins; gastric cancer; infiltrative gastric ... See more keywords