Generation of the Acute Phencyclidine Rat Model for Proteomic Studies of Schizophrenia.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-52479-5_23
Abstract: Administration of the non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist phencyclidine (PCP) to rodents has been used as the gold standard preclinical model for schizophrenia. PCP treatment induces hyperlocomotion and stereotypic behaviour, which resemble the positive symptoms… read more here.
Keywords: model; acute phencyclidine; generation acute; proteomic studies ... See more keywords
LC-MSE for Qualitative and Quantitative Proteomic Studies of Psychiatric Disorders.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-52479-5_7
Abstract: This chapter describes the advantages and disadvantages of label-free liquid chromatography mass spectrometry in data-independent analysis mode (LC-MSE) in the identification of disease biomarkers in studies of psychiatric disorders. Along with the description of the… read more here.
Keywords: quantitative proteomic; psychiatric disorders; qualitative quantitative; mse qualitative ... See more keywords
Proteomic studies on lactic acid bacteria: A review
Sign Up to like & getrecommendations! Published in 2018 at "Biochemistry and Biophysics Reports"
DOI: 10.1016/j.bbrep.2018.04.009
Abstract: Probiotics are amongst the most common microbes in the gastro-intestinal tract of humans and other animals. Prominent among probiotics are Lactobacillus and Bifidobacterium. They offer wide-ranging health promoting benefits to the host which include reduction… read more here.
Keywords: studies lactic; bacteria review; role; acid bacteria ... See more keywords
Revealing new insights into different phosphorus-starving responses between two maize (Zea mays) inbred lines by transcriptomic and proteomic studies
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep44294
Abstract: Phosphorus (P) is an essential plant nutrient, and deficiency of P is one of the most important factors restricting maize yield. Therefore, it is necessary to develop a more efficient program of P fertilization and… read more here.
Keywords: phosphorus; transcriptomic proteomic; revealing new; new insights ... See more keywords
Proteomic studies of common chronic pain conditions - a systematic review and associated network analyses
Sign Up to like & getrecommendations! Published in 2020 at "Expert Review of Proteomics"
DOI: 10.1080/14789450.2020.1797499
Abstract: ABSTRACT Introduction The lack of biomarkers indicating involved nociceptive and/or pain mechanisms makes diagnostic procedures problematic. Clinical pain research has begun to use proteomics. Areas covered This systematic review covers proteomic studies of chronic pain… read more here.
Keywords: pain; review; network analyses; chronic pain ... See more keywords
Merging clinical chemistry biomarker data with a COPD database - building a clinical infrastructure for proteomic studies
Sign Up to like & getrecommendations! Published in 2017 at "Proteome Science"
DOI: 10.1186/s12953-017-0116-2
Abstract: BackgroundData from biological samples and medical evaluations plays an essential part in clinical decision making. This data is equally important in clinical studies and it is critical to have an infrastructure that ensures that its… read more here.
Keywords: biomarker data; chemistry; infrastructure; copd ... See more keywords
Diagnostics and correction of batch effects in large‐scale proteomic studies: a tutorial
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Systems Biology"
DOI: 10.15252/msb.202110240
Abstract: Advancements in mass spectrometry‐based proteomics have enabled experiments encompassing hundreds of samples. While these large sample sets deliver much‐needed statistical power, handling them introduces technical variability known as batch effects. Here, we present a step‐by‐step… read more here.
Keywords: batch effects; diagnostics correction; biology; batch ... See more keywords
Quantitative proteomic studies addressing unmet clinical needs in sarcoma
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1126736
Abstract: Sarcoma is a rare and complex disease comprising over 80 malignant subtypes that is frequently characterized by poor prognosis. Challenges in clinical management include uncertainties in diagnosis and disease classification, limited prognostic and predictive biomarkers,… read more here.
Keywords: quantitative proteomic; studies addressing; sarcoma; disease ... See more keywords
Proteomic Studies to Understand the Mechanisms of Peach Tissue Degradation by Monilinia laxa
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2020.01286
Abstract: Monilinia laxa is a necrotrophic plant pathogen able to infect and produce substantial losses on stone fruit. Three different isolates of M. laxa were characterized according to their aggressiveness on nectarines. M. laxa 8L isolate… read more here.
Keywords: monilinia laxa; studies understand; proteomic studies; tissue ... See more keywords
Polyphenols from Thinned Young Apples: HPLC-HRMS Profile and Evaluation of Their Anti-Oxidant and Anti-Inflammatory Activities by Proteomic Studies
Sign Up to like & getrecommendations! Published in 2022 at "Antioxidants"
DOI: 10.3390/antiox11081577
Abstract: The qualitative profile of thinned apple polyphenols (TAP) fraction (≈24% of polyphenols) obtained by purification through absorbent resin was fully investigated by LC-HRMS in positive and negative ion mode and using ESI source. A total… read more here.
Keywords: inflammatory activities; polyphenols thinned; anti inflammatory; inflammatory ... See more keywords
Proteomic Studies of Psoriasis
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10030619
Abstract: In this review paper, we discuss the contribution of proteomic studies to the discovery of disease-specific biomarkers to monitor the disease and evaluate available treatment options for psoriasis. Psoriasis is one of the most prevalent… read more here.
Keywords: proteomic studies; disease; etiology; studies psoriasis ... See more keywords