Isotopic Labeling and Quantitative Proteomics of Acetylation on Histones and Beyond.
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DOI: 10.1007/978-1-4939-9232-4_5
Abstract: Lysine acetylation is an important posttranslational modification (PTM) that regulates the function of proteins by affecting their localization, stability, binding, and enzymatic activity. Aberrant acetylation patterns have been observed in numerous diseases, most notably cancer,… read more here.
Keywords: labeling quantitative; acetylation; acetylation histones; proteomics acetylation ... See more keywords