Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti-AChR Antibody-Positive Myasthenia Gravis: FGF-19 as a Novel Biomarker.
Sign Up to like & getrecommendations! Published in 2025 at "Annals of clinical and translational neurology"
DOI: 10.1002/acn3.70261
Abstract: OBJECTIVE This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. METHODS We analyzed the… read more here.
Keywords: treatment; proteomics analysis; myasthenia gravis; efg treatment ... See more keywords
Clinical Proteomics for the Analysis of Circulating Extracellular Vesicles.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1178-4_2
Abstract: In recent years, technical improvements in proteomics have allowed its rapid application for biomarker discovery, new drug target identification, and the study of disease progression and drug resistance. The clinical potential of circulating extracellular vesicles… read more here.
Keywords: extracellular vesicles; clinical proteomics; circulating extracellular; study ... See more keywords
Proteomics Analysis of the Estrogen Effects in the Rat Uterus Using Gel-LC and Tandem Mass Spectrometry Approaches.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1920-9_17
Abstract: Proteomics-based bottoms-up, at a big scale applied to the protein identification and relative quantification present in complex mixtures (cell lysates, tissues, biological fluids, secretome, etc.) is a useful strategy to identify proteins and analyze their… read more here.
Keywords: analysis; mass spectrometry; mass; proteomics analysis ... See more keywords
Proteomics Analysis of Myelin Composition.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7862-5_6
Abstract: The identification and functional characterization of the repertoire of myelin proteins provides a valuable foundation for understanding molecular mechanisms of myelination and the pathogenesis of human myelin disease. Here we provide a procedure for the… read more here.
Keywords: analysis myelin; proteomics analysis; biology; myelin composition ... See more keywords
Nianrong Sun and Chunhui Deng: Magnetic micro-/nano-materials for proteomics analysis
Sign Up to like & getrecommendations! Published in 2022 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-022-04067-7
Abstract: Mass spectrometry (MS)-based proteomics has contributed hugely to the determination of the human proteome, which mainly benefits the construction of high-efficiency enzyme reactors and high-performance separation and enrichment methods of proteins prior to MS analysis.… read more here.
Keywords: proteomics analysis; magnetic micro; micro nano; materials proteomics ... See more keywords
A quantitative yeast aging proteomics analysis reveals novel aging regulators.
Sign Up to like & getrecommendations! Published in 2021 at "GeroScience"
DOI: 10.1007/s11357-021-00412-3
Abstract: Calorie restriction (CR) is the most robust longevity intervention, extending lifespan from yeast to mammals. Numerous conserved pathways regulating aging and mediating CR have been identified; however, the overall proteomic changes during these conditions remain… read more here.
Keywords: analysis reveals; aging proteomics; proteomics analysis; quantitative yeast ... See more keywords
Quantitative proteomics analysis of sporadic parathyroid adenoma tissue samples
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Endocrinological Investigation"
DOI: 10.1007/s40618-018-0958-1
Abstract: ObjectiveMolecular pathogenesis of parathyroid tumors is incompletely understood. Identification of novel molecules and understanding their role in parathyroid tumorigenesis by proteomics approach would be informative with potential clinical implications.MethodAdenomatous (n = 5) and normal (n = 2) parathyroid tissue… read more here.
Keywords: analysis sporadic; analysis; parathyroid; tissue ... See more keywords
Comprehensive Proteomics Analysis of Stressed Human Islets Identifies GDF15 as a Target for Type 1 Diabetes Intervention.
Sign Up to like & getrecommendations! Published in 2020 at "Cell metabolism"
DOI: 10.1016/j.cmet.2019.12.005
Abstract: Type 1 diabetes (T1D) results from the progressive loss of β cells, a process propagated by pro-inflammatory cytokine signaling that disrupts the balance between pro- and anti-apoptotic proteins. To identify proteins involved in this process,… read more here.
Keywords: comprehensive proteomics; human islets; target; proteomics analysis ... See more keywords
Effects of super-chilling storage on shelf-life and quality indicators of Coregonus peled based on proteomics analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Food research international"
DOI: 10.1016/j.foodres.2021.110229
Abstract: The advantages of super-chilling storage at -2 °C for maintaining the quality of Coregonus peled muscle were investigated using the rigor-mortis index (RM), ATP-related compounds, K-value, muscle hardness, impedance measurement, and total viable count. The results… read more here.
Keywords: muscle; proteomics analysis; chilling storage; super chilling ... See more keywords
Proteomics analysis and its role in elucidation of functionally significant proteins in Mycoplasma bovis.
Sign Up to like & getrecommendations! Published in 2017 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2017.08.024
Abstract: Mycoplasma bovis (M. bovis) is an emerging devastating cause of pneumonia in dairy and feedlot calves around the world, largely due to its increasing resistance to new generation effective antibiotics and lack of efficient vaccine. Failure… read more here.
Keywords: bovis; proteomics analysis; proteins bovis; role ... See more keywords
A comparative proteomics analysis of the egg secretions of three major schistosome species.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular and biochemical parasitology"
DOI: 10.1016/j.molbiopara.2020.111322
Abstract: Morbidity associated with hepatic and urogenital schistosomiasis stems primarily from the host immune response directed against schistosome eggs. When eggs become entrapped in host tissues, the development of fibrotic plaques drives downstream pathology. These events… read more here.
Keywords: mansoni japonicum; egg secretions; proteomics analysis; egg ... See more keywords