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Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1178-4_2
Abstract: In recent years, technical improvements in proteomics have allowed its rapid application for biomarker discovery, new drug target identification, and the study of disease progression and drug resistance. The clinical potential of circulating extracellular vesicles…
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Keywords:
extracellular vesicles;
clinical proteomics;
circulating extracellular;
study ... See more keywords
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Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1920-9_17
Abstract: Proteomics-based bottoms-up, at a big scale applied to the protein identification and relative quantification present in complex mixtures (cell lysates, tissues, biological fluids, secretome, etc.) is a useful strategy to identify proteins and analyze their…
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Keywords:
analysis;
mass spectrometry;
mass;
proteomics analysis ... See more keywords
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Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7862-5_6
Abstract: The identification and functional characterization of the repertoire of myelin proteins provides a valuable foundation for understanding molecular mechanisms of myelination and the pathogenesis of human myelin disease. Here we provide a procedure for the…
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Keywords:
analysis myelin;
proteomics analysis;
biology;
myelin composition ... See more keywords
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Published in 2022 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-022-04067-7
Abstract: Mass spectrometry (MS)-based proteomics has contributed hugely to the determination of the human proteome, which mainly benefits the construction of high-efficiency enzyme reactors and high-performance separation and enrichment methods of proteins prior to MS analysis.…
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Keywords:
proteomics analysis;
magnetic micro;
micro nano;
materials proteomics ... See more keywords
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Published in 2021 at "GeroScience"
DOI: 10.1007/s11357-021-00412-3
Abstract: Calorie restriction (CR) is the most robust longevity intervention, extending lifespan from yeast to mammals. Numerous conserved pathways regulating aging and mediating CR have been identified; however, the overall proteomic changes during these conditions remain…
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Keywords:
analysis reveals;
aging proteomics;
proteomics analysis;
quantitative yeast ... See more keywords
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Published in 2018 at "Journal of Endocrinological Investigation"
DOI: 10.1007/s40618-018-0958-1
Abstract: ObjectiveMolecular pathogenesis of parathyroid tumors is incompletely understood. Identification of novel molecules and understanding their role in parathyroid tumorigenesis by proteomics approach would be informative with potential clinical implications.MethodAdenomatous (n = 5) and normal (n = 2) parathyroid tissue…
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Keywords:
analysis sporadic;
analysis;
parathyroid;
tissue ... See more keywords
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Published in 2020 at "Cell metabolism"
DOI: 10.1016/j.cmet.2019.12.005
Abstract: Type 1 diabetes (T1D) results from the progressive loss of β cells, a process propagated by pro-inflammatory cytokine signaling that disrupts the balance between pro- and anti-apoptotic proteins. To identify proteins involved in this process,…
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Keywords:
comprehensive proteomics;
human islets;
target;
proteomics analysis ... See more keywords
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Published in 2021 at "Food research international"
DOI: 10.1016/j.foodres.2021.110229
Abstract: The advantages of super-chilling storage at -2 °C for maintaining the quality of Coregonus peled muscle were investigated using the rigor-mortis index (RM), ATP-related compounds, K-value, muscle hardness, impedance measurement, and total viable count. The results…
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Keywords:
muscle;
proteomics analysis;
chilling storage;
super chilling ... See more keywords
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Published in 2017 at "Microbial pathogenesis"
DOI: 10.1016/j.micpath.2017.08.024
Abstract: Mycoplasma bovis (M. bovis) is an emerging devastating cause of pneumonia in dairy and feedlot calves around the world, largely due to its increasing resistance to new generation effective antibiotics and lack of efficient vaccine. Failure…
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Keywords:
bovis;
proteomics analysis;
proteins bovis;
role ... See more keywords
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Published in 2020 at "Molecular and biochemical parasitology"
DOI: 10.1016/j.molbiopara.2020.111322
Abstract: Morbidity associated with hepatic and urogenital schistosomiasis stems primarily from the host immune response directed against schistosome eggs. When eggs become entrapped in host tissues, the development of fibrotic plaques drives downstream pathology. These events…
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Keywords:
mansoni japonicum;
egg secretions;
proteomics analysis;
egg ... See more keywords
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Published in 2020 at "South African Journal of Botany"
DOI: 10.1016/j.sajb.2019.08.056
Abstract: Abstract Every year 15 million babies are born prematurely worldwide and a million of these infants die. We know that bacterial infections are associated with and are the primary cause of preterm labor. Unfortunately, current…
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Keywords:
oleifera;
moringa oleifera;
escherichia coli;
proteomics analysis ... See more keywords