A proteomics approach to decipher a sticky CHO situation
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28108
Abstract: Chinese hamster ovary (CHO) cells serve as protein therapeutics workhorses, so it is useful to understand what intrinsic properties make certain host cell lines and clones preferable for scale up and production of target proteins.… read more here.
Keywords: cell; approach decipher; proteomics approach; decipher sticky ... See more keywords
Comparative Proteomics Studies of Insect Cuticle by Tandem Mass Spectrometry: Application of a Novel Proteomics Approach to the Pea Aphid Cuticular Proteins
Sign Up to like & getrecommendations! Published in 2018 at "PROTEOMICS"
DOI: 10.1002/pmic.201700368
Abstract: The cuticle is a biological composite material consisting principally of N‐acetylglucosamine polymer embedded in cuticular proteins (CPs). CPs have been studied and characterized by mass spectrometry in several cuticular structures and in many arthropods. Such… read more here.
Keywords: proteomics approach; novel proteomics; mass spectrometry; cuticular proteins ... See more keywords
iTRAQ-Based Shotgun Proteomics Approach for Relative Protein Quantification.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6730-8_23
Abstract: Shotgun proteomics has a key role in quantitative estimation of proteins from biological systems under different conditions, which is crucial in the understanding of their functional roles. Isobaric tagging for relative and absolute quantitation (iTRAQ)… read more here.
Keywords: proteomics approach; based shotgun; itraq; quantification ... See more keywords
A targeted proteomics approach to amyloidosis typing
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Mass Spectrometry"
DOI: 10.1016/j.clinms.2018.02.001
Abstract: Abstract Background Amyloidosis is a life threatening disease caused by deposition of various types of blood serum proteins in organs and tissues. Knowing the type of protein involved is the basis of a correct diagnosis… read more here.
Keywords: proteomics approach; protein; tissue; targeted proteomics ... See more keywords
Sub-fertility in crossbred bulls: Identification of proteomic alterations in spermatogenic cells using high throughput comparative proteomics approach.
Sign Up to like & getrecommendations! Published in 2021 at "Theriogenology"
DOI: 10.1016/j.theriogenology.2021.04.012
Abstract: The present study was carried out to compare the proteomic profiles of spermatogenic cells of crossbred and zebu cattle in an effort to understand the possible reasons for a higher incidence of sub-fertility in crossbred… read more here.
Keywords: protein; proteomics approach; fertility crossbred; spermatogenic cells ... See more keywords
Determination of the Time since Deposition of Blood Traces Utilizing a Liquid Chromatography-Mass Spectrometry-Based Proteomics Approach.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c01009
Abstract: Knowledge about when a bloodstain was deposited at a crime scene can be of critical value in forensic investigation. A donor of a genetically identified bloodstain could be linked to a suspected time frame and… read more here.
Keywords: time; since deposition; proteomics approach; determination time ... See more keywords
Unraveling the Neuroprotective Effect of Tinospora cordifolia in a Parkinsonian Mouse Model through the Proteomics Approach.
Sign Up to like & getrecommendations! Published in 2021 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.1c00481
Abstract: Stress-induced dopaminergic (DAergic) neuronal death in the midbrain region is the primary cause of Parkinson's disease (PD). Following the discovery of l-dopa, multiple drugs have been developed to improve the lifestyle of PD patients; however,… read more here.
Keywords: proteomics approach; neuroprotective effect; unraveling neuroprotective; mouse model ... See more keywords
Split-BioID a conditional proteomics approach to monitor the composition of spatiotemporally defined protein complexes
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/ncomms15690
Abstract: Understanding the function of the thousands of cellular proteins is a central question in molecular cell biology. As proteins are typically part of multiple dynamic and often overlapping macromolecular complexes exerting distinct functions, the identification… read more here.
Keywords: protein; proteomics approach; bioid conditional; spatiotemporally defined ... See more keywords
In‐depth proteomics approach reveals novel biomarkers of cardiac remodelling after myocardial infarction: An exploratory analysis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.15611
Abstract: Cardiac remodelling following myocardial infarction (MI) is a maladaptive change associated with progressive heart failure and compromises long‐term clinical outcome. A substantial proportion of patients afflicted by MI still develop adverse outcomes associated with cardiac… read more here.
Keywords: proteomics approach; cardiac remodelling; myocardial infarction; depth proteomics ... See more keywords
A targeted multi-proteomics approach generates a blueprint of the ciliary ubiquitinome
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2023.1113656
Abstract: Establishment and maintenance of the primary cilium as a signaling-competent organelle requires a high degree of fine tuning, which is at least in part achieved by a variety of post-translational modifications. One such modification is… read more here.
Keywords: blueprint ciliary; proteomics approach; ciliary ubiquitinome; ubiquitination ... See more keywords
Proteomics approach to investigating osmotic stress effects on pistachio
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.1041649
Abstract: Osmotic stress can occur due to some stresses such as salinity and drought, threatening plant survival. To investigate the mechanism governing the pistachio response to this stress, the biochemical alterations and protein profile of PEG-treated… read more here.
Keywords: stress; osmotic stress; proteomics approach; approach investigating ... See more keywords