Discovery of potential ferroptosis and osteoporosis biomarkers through TMT proteomics and bioinformatics analysis
Sign Up to like & getrecommendations! Published in 2024 at "BioMedical Engineering OnLine"
DOI: 10.1186/s12938-024-01307-y
Abstract: Primary osteoporosis has increasingly emerged as a major issue affecting human health, with a complex specific pathogenic mechanism. As a research hotspot, ferroptosis plays a vital role in the pathogenesis of primary osteoporosis, aiming to… read more here.
Keywords: tmt proteomics; analysis; ferroptosis; osteoporosis ... See more keywords
Analysis and validation of serum biomarkers in brucellosis patients through proteomics and bioinformatics
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2024.1446339
Abstract: Introduction This study aims to utilize proteomics, bioinformatics, and machine learning algorithms to identify diagnostic biomarkers in the serum of patients with acute and chronic brucellosis Methods Proteomic analysis was conducted on serum samples from… read more here.
Keywords: biomarkers brucellosis; analysis; validation; expression ... See more keywords
An Integrated Proteomics and Bioinformatics Approach Reveals the Anti-inflammatory Mechanism of Carnosic Acid
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2018.00370
Abstract: Drastic macrophages activation triggered by exogenous infection or endogenous stresses is thought to be implicated in the pathogenesis of various inflammatory diseases. Carnosic acid (CA), a natural phenolic diterpene extracted from Salvia officinalis plant, has… read more here.
Keywords: anti inflammatory; mechanism; bioinformatics approach; proteomics bioinformatics ... See more keywords
Discovery of Proteins Responsible for Resistance to Three Chemotherapy Drugs in Breast Cancer Cells Using Proteomics and Bioinformatics Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27061762
Abstract: Chemoresistance is a daunting obstacle to the effective treatment of breast cancer patients receiving chemotherapy. Although the mechanism of chemotherapy drug resistance has been explored broadly, the precise mechanism at the proteome level remains unclear.… read more here.
Keywords: bioinformatics analysis; proteomics bioinformatics; breast cancer; resistance ... See more keywords