Discovery and Validation of Clinical Biomarkers of Cancer: A Review Combining Metabolomics and Proteomics
Sign Up to like & getrecommendations! Published in 2019 at "PROTEOMICS"
DOI: 10.1002/pmic.201700448
Abstract: Early detection and diagnosis of cancer can allow timely medical intervention, which greatly improves chances of survival and enhances quality of life. Biomarkers play an important role in assisting clinicians and health care providers in… read more here.
Keywords: validation; validation clinical; review; cancer ... See more keywords
Stroke Proteomics: From Discovery to Diagnostic and Therapeutic Applications.
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DOI: 10.1161/circresaha.122.320110
Abstract: Stroke remains a leading cause of death and disability, with limited therapeutic options and suboptimal tools for diagnosis and prognosis. High throughput technologies such as proteomics generate large volumes of experimental data at once, thus… read more here.
Keywords: discovery diagnostic; proteomics discovery; stroke proteomics; diagnostic therapeutic ... See more keywords
From proteomics to discovery of first-in-class ST2 inhibitors active in vivo.
Sign Up to like & getrecommendations! Published in 2018 at "JCI insight"
DOI: 10.1172/jci.insight.99208
Abstract: Soluble cytokine receptors function as decoy receptors to attenuate cytokine-mediated signaling and modulate downstream cellular responses. Dysregulated overproduction of soluble receptors can be pathological, such as soluble ST2 (sST2), a prognostic biomarker in cardiovascular diseases,… read more here.
Keywords: vivo; st2 inhibitors; discovery first; proteomics discovery ... See more keywords
Application of Proteomics in the Discovery of Radiosensitive Cancer Biomarkers
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.852791
Abstract: Radiation therapy remains an important component of cancer treatment. Gene-encoded proteins were the actual executors of cellular functions. Proteomic was a novel technology that can systematically analysis protein composition and measure their levels of change,… read more here.
Keywords: cancer; application proteomics; discovery radiosensitive; radiosensitive cancer ... See more keywords