Proximity proteomics identifies septins and PAK2 as decisive regulators of actomyosin-mediated expulsion of von Willebrand factor
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DOI: 10.1182/blood.2022017419
Abstract: Key Points • Proximity proteomics and siRNA subscreens in endothelial cells reveal proteins associated with regulated actomyosin expulsion of VWF.• PAK2 and septin hetero-oligomeric complexes are required for actomyosin ring function and effective VWF release. read more here.
Keywords: proteomics identifies; expulsion; identifies septins; proximity ... See more keywords