Integrated Proteomics and Metabolomics Reveal the Mechanism of Nephrotoxicity Induced by Triptolide.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical research in toxicology"
DOI: 10.1021/acs.chemrestox.0c00091
Abstract: Triptolide (TP), the main active ingredient of Tripterygium wilfordii Hook F., has great potential in the treatment of autoimmune diseases. However, it has been found that the side effects of TP involve multiple organs and… read more here.
Keywords: mechanism; proteomics metabolomics; metabolism; integrated proteomics ... See more keywords
Integrated Proteomics and Metabolomics Analysis Correlative Metabolite-Protein Networks in Soybean Seeds Subjected to Warm-Water Soaking.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.0c00986
Abstract: Soaking of soybean seeds is prerequisite for the production of soy foods and it has been shown that the extent of water absorbed during different imbibition conditions directly affects the quality of the subsequent soybean… read more here.
Keywords: seed; proteomics metabolomics; soybean seeds; water ... See more keywords
Proteomics and metabolomics for analysis of the dynamics of microbiota
Sign Up to like & getrecommendations! Published in 2018 at "Expert Review of Proteomics"
DOI: 10.1080/14789450.2018.1421073
Abstract: Infectious diseases and associated antibiotic resistance are two medical scourges in need of better laboratory diagnostics. Despite a current developmental focus on molecular testing including metagenomic nucleic acid sequencing, many alternative technologies need to be… read more here.
Keywords: proteomics metabolomics; analysis; analysis dynamics; microbiology ... See more keywords
Integrated proteomics and metabolomics analysis of transgenic and gene-stacked maize line seeds
Sign Up to like & getrecommendations! Published in 2021 at "GM Crops & Food"
DOI: 10.1080/21645698.2021.1934351
Abstract: ABSTRACT Unintended effects of genetically modified (GM) crops may pose safety issues. Omics techniques provide researchers with useful tools to assess such unintended effects. Proteomics and metabolomics analyses were performed for three GM maize varieties,… read more here.
Keywords: zheng58 zheng58; proteomics metabolomics; analysis; integrated proteomics ... See more keywords
The role of proteomics and metabolomics in severe infections
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Critical Care"
DOI: 10.1097/mcc.0000000000000966
Abstract: Purpose of review Severe infections are a common cause of ICU admission, with a high morbidity and mortality. Omics, namely proteomics and metabolomics, aim to identify, characterize, and quantify biological molecules to achieve a systems-level… read more here.
Keywords: metabolomics severe; proteomics metabolomics; disease; severe infections ... See more keywords
The ‘-ics’ of male reproduction: genomics, epigenetics, proteomics, metabolomics, and microbiomics
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Urology"
DOI: 10.1097/mou.0000000000001052
Abstract: Purpose of review To review the most current findings, from the past 2 years, in various ‘-ics’ fields in male infertility, with a specific focus on nonobstructive azoospermia, the most severe form, and varicocele, the… read more here.
Keywords: genomics epigenetics; epigenetics proteomics; ics male; proteomics metabolomics ... See more keywords
Proteomics and metabolomics of HIV‐associated neurocognitive disorders: A systematic review
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Neurochemistry"
DOI: 10.1111/jnc.15295
Abstract: HIV‐associated neurocognitive disorders (HAND) are common features of the effect of human immunodeficiency virus (HIV)‐1 within the central nervous system (CNS). The underlying neuropathophysiology of HAND is incompletely known. Furthermore, there are no markers to… read more here.
Keywords: proteomics metabolomics; systematic review; hand; neurocognitive disorders ... See more keywords
Proteomics and Metabolomics Studies on the Biotic Stress Responses of Rice: an Update
Sign Up to like & getrecommendations! Published in 2021 at "Rice"
DOI: 10.1186/s12284-021-00461-4
Abstract: Biotic stresses represent a serious threat to rice production to meet global food demand and thus pose a major challenge for scientists, who need to understand the intricate defense mechanisms. Proteomics and metabolomics studies have… read more here.
Keywords: rice; proteomics metabolomics; responses rice; stress ... See more keywords
Analysis of the mechanism of Ricinus communis L. tolerance to Cd metal based on proteomics and metabolomics
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0272750
Abstract: The pollution of soil with heavy metals is an increasingly serious worldwide problem, and cadmium (Cd) has attracted attention because of its high toxicity to almost all plants. Since castor tolerates the accumulation of heavy… read more here.
Keywords: castor; proteomics metabolomics; analysis; tolerance ... See more keywords
Mitochondrial Inorganic Polyphosphate (polyP) Is a Potent Regulator of Mammalian Bioenergetics in SH-SY5Y Cells: A Proteomics and Metabolomics Study
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.833127
Abstract: Inorganic polyphosphate (polyP) is an ancient, ubiquitous, and well-conserved polymer which is present in all the studied organisms. It is formed by individual subunits of orthophosphate which are linked by structurally similar bonds and isoenergetic… read more here.
Keywords: polyphosphate polyp; inorganic polyphosphate; physiology; polyp ... See more keywords
Integrated analysis of transcriptomics, proteomics and metabolomics data reveals the role of SLC39A1 in renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.977960
Abstract: Purpose: Accumulating evidence suggests that solute carrier family 39 member 1 (SLC39A1) conceivably function as a tumor suppressor, but the underlying mechanism in renal cell carcinoma (RCC) is poorly understood. Methods: OSRC-2 renal cancer cells… read more here.
Keywords: cell; cell carcinoma; metabolism; renal cell ... See more keywords