Proteomics profiling reveals a distinct high-risk molecular subtype of hypertrophic cardiomyopathy
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DOI: 10.1136/heartjnl-2021-320729
Abstract: Objective Hypertrophic cardiomyopathy (HCM) is a heterogeneous disease, likely encompassing several subtypes of disease with distinct biological mechanisms (ie, molecular subtypes). Current models based solely on clinical data have yielded limited accuracy in predicting the… read more here.
Keywords: hypertrophic cardiomyopathy; molecular subtypes; risk; proteomics profiling ... See more keywords
Comprehensive Proteomics Profiling Identifies Patients With Late Gadolinium Enhancement on Cardiac Magnetic Resonance Imaging in the Hypertrophic Cardiomyopathy Population
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DOI: 10.3389/fcvm.2022.839409
Abstract: Introduction In hypertrophic cardiomyopathy (HCM), late gadolinium enhancement (LGE) on cardiac magnetic resonance imaging (CMR) represents myocardial fibrosis and is associated with sudden cardiac death. However, CMR requires particular expertise and is expensive and time-consuming.… read more here.
Keywords: magnetic resonance; hypertrophic cardiomyopathy; late gadolinium; cardiac magnetic ... See more keywords
Possibilities of Proteomics Profiling in Predicting Dysfunction of the Cardiovascular System
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DOI: 10.3389/fphys.2022.897694
Abstract: In our opinion, cardiovascular proteomics is the most perspective field of proteomic research in space and Earth medicine. Proteomics, being still a relatively new discipline of fundamental research, is becoming not only a methodology for… read more here.
Keywords: cardiovascular system; system; profiling predicting; cardiovascular ... See more keywords