Quantitative Proteomics Reveal the Role of Matrine in Regulating Lipid Metabolism
Sign Up to like & getrecommendations! Published in 2024 at "ACS Omega"
DOI: 10.1021/acsomega.3c09983
Abstract: Hyperlipidemia (HLP) is a prevalent systemic metabolic disorder characterized by disrupted lipid metabolism. Statin drugs have long been the primary choice for managing lipid levels, but intolerance issues have prompted the search for alternative treatments.… read more here.
Keywords: role; lipid metabolism; quantitative proteomics; metabolism ... See more keywords
Chemical proteomics reveal CD147 as a functional target of pseudolaric acid B in human cancer cells.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical communications"
DOI: 10.1039/c7cc04345g
Abstract: CD147 is a glycosylated transmembrane protein highly expressed on the surface of various tumor cells which plays vital roles in tumor invasion, progression and metastasis. We report the discovery of the natural product pseudolaric acid… read more here.
Keywords: reveal cd147; pseudolaric acid; functional target; chemical proteomics ... See more keywords
Abstract 7100: Quantitative proteomics reveal the mechanism of TTFields therapy for glioblastoma
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Research"
DOI: 10.1158/1538-7445.am2024-7100
Abstract: Glioblastoma (GBM) is a highly malignant brain tumor, and conventional treatments such as surgical resection and chemotherapy have limited effectiveness, with a high rate of recurrence and poor prognosis for patients. In 2011, the FDA… read more here.
Keywords: quantitative proteomics; glioblastoma; proteomics reveal; ttfields treatment ... See more keywords
Integrated Quantitative Targeted Lipidomics and Proteomics Reveal Unique Fingerprints of Multiple Metabolic Conditions
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12101439
Abstract: Aberrations in lipid and lipoprotein metabolic pathways can lead to numerous diseases, including cardiovascular disease, diabetes, neurological disorders, and cancer. The integration of quantitative lipid and lipoprotein profiling of human plasma may provide a powerful… read more here.
Keywords: targeted lipidomics; proteomics reveal; quantitative targeted; lipidomics proteomics ... See more keywords