Chemical proteomics reveal CD147 as a functional target of pseudolaric acid B in human cancer cells.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical communications"
DOI: 10.1039/c7cc04345g
Abstract: CD147 is a glycosylated transmembrane protein highly expressed on the surface of various tumor cells which plays vital roles in tumor invasion, progression and metastasis. We report the discovery of the natural product pseudolaric acid… read more here.
Keywords: reveal cd147; pseudolaric acid; functional target; chemical proteomics ... See more keywords
Integrated Quantitative Targeted Lipidomics and Proteomics Reveal Unique Fingerprints of Multiple Metabolic Conditions
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12101439
Abstract: Aberrations in lipid and lipoprotein metabolic pathways can lead to numerous diseases, including cardiovascular disease, diabetes, neurological disorders, and cancer. The integration of quantitative lipid and lipoprotein profiling of human plasma may provide a powerful… read more here.
Keywords: targeted lipidomics; proteomics reveal; quantitative targeted; lipidomics proteomics ... See more keywords