Articles with "proteopathic tau" as a keyword



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Two simple assays for assessing the seeding activity of proteopathic tau

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Published in 2023 at "Frontiers in Aging Neuroscience"

DOI: 10.3389/fnagi.2023.1073774

Abstract: The regional distribution of neurofibrillary tangles of hyperphosphorylated tau aggregates is associated with the progression of Alzheimer’s disease (AD). Misfolded proteopathic tau recruits naïve tau and templates its misfolding and aggregation in a prion-like fashion,… read more here.

Keywords: seeding activity; aggregation; proteopathic tau; two simple ... See more keywords