Application of Phosphoramidate ProTide Technology for the Synthesis of 5’‐mRNA Cap Analogs Modified on the Exocyclic Amine Group
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DOI: 10.1002/cmdc.202200490
Abstract: Aryloxy triester phosphoramidate methodology, commonly known as ProTide technology, is one of the most widely used prodrug approaches applied to therapeutic nucleosides. This approach has been used extensively by the pharmaceutical industry and researchers in… read more here.
Keywords: cap; synthesis; protide technology; mrna cap ... See more keywords