Cochrane Qualitative and Implementation Methods Group guidance series-paper 2: methods for question formulation, searching, and protocol development for qualitative evidence synthesis.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of clinical epidemiology"
DOI: 10.1016/j.jclinepi.2017.10.023
Abstract: This paper updates previous Cochrane guidance on question formulation, searching, and protocol development, reflecting recent developments in methods for conducting qualitative evidence syntheses to inform Cochrane intervention reviews. Examples are used to illustrate how decisions about… read more here.
Keywords: question; evidence; protocol development; question formulation ... See more keywords
Protocol for the development of SPIRIT and CONSORT extensions for randomised controlled trials with surrogate primary endpoints: SPIRIT-SURROGATE and CONSORT-SURROGATE
Sign Up to like & getrecommendations! Published in 2022 at "BMJ Open"
DOI: 10.1136/bmjopen-2022-064304
Abstract: Introduction Randomised controlled trials (RCTs) may use surrogate endpoints as substitutes and predictors of patient-relevant/participant-relevant final outcomes (eg, survival, health-related quality of life). Translation of effects measured on a surrogate endpoint into health benefits for… read more here.
Keywords: protocol development; controlled trials; randomised controlled; consort ... See more keywords
Protocol development for discovery of angiogenesis inhibitors via automated methods using zebrafish
Sign Up to like & getrecommendations! Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0221796
Abstract: Their optical clarity as larvae and embryos, small size, and high fecundity make zebrafish ideal for whole animal high throughput screening. A high-throughput drug discovery platform (HTP) has been built to perform fully automated screens… read more here.
Keywords: angiogenesis; angiogenesis inhibitors; discovery angiogenesis; protocol development ... See more keywords
Androgenesis-Based Doubled Haploidy: Past, Present, and Future Perspectives
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2021.751230
Abstract: Androgenesis, which entails cell fate redirection within the microgametophyte, is employed widely for genetic gain in plant breeding programs. Moreover, androgenesis-responsive species provide tractable systems for studying cell cycle regulation, meiotic recombination, and apozygotic embryogenesis… read more here.
Keywords: based doubled; protocol development; androgenesis; androgenesis based ... See more keywords