Stereodivergent Asymmetric Synthesis of α,β-Disubstituted β Aminoalkylboronic Acid Derivatives via Group-Selective Protodeboronation Enabling Access to the Elusive anti Isomer.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.0c03207
Abstract: Chiral β-aminoalkylboronates generate growing interest as versatile synthetic building blocks to access β-aminoalcohols and other useful compounds, and also as bioisosteres of β-aminoacids in drug discovery. In this study, the lack of methodology to access… read more here.
Keywords: elusive anti; anti isomer; protodeboronation; group ... See more keywords
Catalytic efficiency of Cu-MOFs: HKUST-1 and CuBDC for the protodeboronation of aryl boronic acids
Sign Up to like & getrecommendations! Published in 2025 at "RSC Advances"
DOI: 10.1039/d5ra04172d
Abstract: This study investigates the catalytic potential of copper-based metal–organic frameworks (Cu-MOFs), specifically HKUST-1 and CuBDC, for the protodeboronation of aryl boronic acids. Protodeboronation, was explored under various bases, atmospheres, and substrates. Optimal conditions using K2CO3… read more here.
Keywords: aryl boronic; protodeboronation; protodeboronation aryl; hkust cubdc ... See more keywords