The current status of pre-clinical proton flash radiation and future directions.
Sign Up to like & getrecommendations! Published in 2021 at "Medical physics"
DOI: 10.1002/mp.15276
Abstract: We review the current status of proton FLASH experimental systems, including pre-clinical physical and biological results. Technological limitations on preclinical investigation of FLASH biological mechanisms and determination of clinically relevant parameters are discussed. A review… read more here.
Keywords: flash; proton flash; current status; proton ... See more keywords
Feasibility study of hybrid inverse planning with transmission beams and single-energy spread-out Bragg peaks for proton FLASH radiotherapy.
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DOI: 10.1002/mp.16370
Abstract: BACKGROUND Ultra-high dose rate (FLASH) proton planning with only transmission beams (TBs) has limitations in normal tissue sparing. The single-energy spread-out Bragg peaks (SESOBPs) of the FLASH dose rate have been demonstrated feasible for proton… read more here.
Keywords: dose rate; sesobp; proton flash; planning ... See more keywords
Verification of dose and dose rate for quality assurance of spread‐out‐Bragg‐peak proton FLASH radiotherapy using machine log files
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DOI: 10.1002/mp.17792
Abstract: Ultra‐high dose rate radiotherapy elicits a biological effect (FLASH), which has been shown to reduce toxicity while maintaining tumor control in preclinical radiobiology experiments. FLASH depends on the dose rate, with evidence that higher dose… read more here.
Keywords: rate; radiotherapy; proton flash; dose rate ... See more keywords