LAUSR

Signaling Pathways in Proton and Non-proton ASIC1a Activation

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1 Published in 2021 at "Frontiers in Cellular Neuroscience"

DOI: 10.3389/fncel.2021.735414

Abstract: Acid-sensing ion channels (ASICs) regulate synaptic activities and play important roles in neurodegenerative diseases as well as pain conditions. Classically, ASICs are described as transiently activated by a reduced pH, followed by desensitization; the activation… read more here.

Keywords: signaling pathways; asic1a; proton; activation ... See more keywords