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Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14518
Abstract: Complex I is a key proton‐pumping enzyme in bacterial and mitochondrial respiratory electron transport chains. Using quantum chemistry and electrostatic calculations, we have examined the pKa of the reduced quinone QH−/QH2 in the catalytic cavity… read more here.
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Published in 2019 at "Journal of inorganic biochemistry"
DOI: 10.1016/j.jinorgbio.2019.110866
Abstract: Cytochrome c oxidases (CcOs) couple the exergonic reduction of molecular oxygen to proton pumping across the membrane in which they are embedded, thereby conserving a significant part of the free energy. The A family CcOs… read more here.
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Published in 2017 at "Nature Communications"
DOI: 10.1038/ncomms14145
Abstract: Ongoing ocean acidification is widely reported to reduce the ability of calcifying marine organisms to produce their shells and skeletons. Whereas increased dissolution due to acidification is a largely inorganic process, strong organismal control over… read more here.
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Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-12746-0
Abstract: We make use of the physical mechanism of proton pumping in the so-called Complex I within mitochondria membranes. Our model is based on sequential charge transfer assisted by conformational changes which facilitate the indirect electron-proton… read more here.
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Published in 2021 at "Chemical Science"
DOI: 10.1039/d0sc06061e
Abstract: The visualization of chloride in living cells with fluorescent sensors is linked to our ability to design hosts that can overcome the energetic penalty of desolvation to bind chloride in water. Fluorescent proteins can be… read more here.
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Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2211018119
Abstract: Photoheterotrophic bacteria harvest light energy using either proton-pumping rhodopsins or bacteriochlorophyll (BChl)-based photosystems. The bacterium Sphingomonas glacialis AAP5 isolated from the alpine lake Gossenköllesee contains genes for both systems. Here, we show that BChl is… read more here.
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Published in 2018 at "Environmental Microbiology"
DOI: 10.1111/1462-2920.14035
Abstract: Proton-pumping rhodopsins provide an alternative pathway to photosynthesis by which solar energy can enter the marine food web. Rhodopsin genes are widely found in marine bacteria, also in the Arctic, and were recently reported from… read more here.
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Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.826990
Abstract: Microbial rhodopsins have recently been discovered in pathogenic fungi and have been postulated to be involved in signaling during the course of an infection. Here, we report on the spectroscopic characterization of a light-driven proton… read more here.
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Published in 2017 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2017.01572
Abstract: Agbiotechnology uses genetic engineering to improve the output and value of crops. Altering the expression of the plant Type I Proton-pumping Pyrophosphatase (H+-PPase) has already proven to be a useful tool to enhance crop productivity.… read more here.