Role of chromatin modulation in the establishment of protozoan parasite infection for developing targeted chemotherapeutics
Sign Up to like & getrecommendations! Published in 2021 at "Nucleus"
DOI: 10.1007/s13237-021-00356-1
Abstract: Four major human infecting protozoan parasites (Plasmodium, Toxoplasma, Leishmania, and Trypanosoma) impose a substantial threat to health and socio-economic status causing significant morbidity and mortality in tropics and subtropics each year. Lack of effective drugs,… read more here.
Keywords: chromatin; role chromatin; protozoan; modulation ... See more keywords
Development and evaluation of a molecular based protocol for detection and quantification of Cryptosporidium spp. In wastewater.
Sign Up to like & getrecommendations! Published in 2022 at "Experimental parasitology"
DOI: 10.1016/j.exppara.2022.108216
Abstract: Infections caused by protozoan parasites are a major public health concern globally. These infections are commonly diagnosed during water-borne outbreaks, necessitating accurate and highly sensitive detection procedures to assure public health protection. Current molecular techniques… read more here.
Keywords: dna; extraction; wastewater; cryptosporidium ... See more keywords
Clearing or subverting the enemy: Role of autophagy in protozoan infections.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.117453
Abstract: The protozoan parasites are evolutionarily divergent, unicellular eukaryotic pathogens representing one of the essential sources of parasitic diseases. These parasites significantly affect the economy and cause public health burdens globally. Protozoan parasites share many cellular… read more here.
Keywords: protozoan; enemy role; subverting enemy; autophagy ... See more keywords
Occurrence of the protozoan parasites Toxoplasma gondii and Cyclospora cayetanensis in the invasive Atlantic blue crab Callinectes sapidus from the Lesina Lagoon (SE Italy).
Sign Up to like & getrecommendations! Published in 2022 at "Marine pollution bulletin"
DOI: 10.1016/j.marpolbul.2022.113428
Abstract: The occurrence of the protozoan parasites Toxoplasma gondii and Cyclospora cayetanensis was molecularly investigated in the hemolymph, gills, stomach, hepatopancreas and gonads of the eleven invasive Atlantic blue crab Callinectes sapidus from the Lesina Lagoon… read more here.
Keywords: crab; protozoan; lagoon; cayetanensis ... See more keywords
Waterborne protozoan outbreaks: An update on the global, regional, and national prevalence from 2017 to 2020 and sources of contamination
Sign Up to like & getrecommendations! Published in 2022 at "Science of The Total Environment"
DOI: 10.1016/j.scitotenv.2021.150562
Abstract: Abstract The aim of this review is to identify the worldwide trend of waterborne protozoan outbreaks and how it varies between geographic regions during the period from 2017 to 2020. Data about waterborne protozoan outbreaks… read more here.
Keywords: protozoan; 2017 2020; protozoan outbreaks; prevalence ... See more keywords
Genetic, metabolomic and transcriptomic analyses of the de novo L-cysteine biosynthetic pathway in the enteric protozoan parasite Entamoeba histolytica
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-15923-3
Abstract: The de novo L-cysteine biosynthetic pathway is critical for the growth, antioxidative stress defenses, and pathogenesis of bacterial and protozoan pathogens, such as Salmonella typhimurium and Entamoeba histolytica. This pathway involves two key enzymes, serine… read more here.
Keywords: protozoan; cysteine biosynthetic; novo cysteine; entamoeba histolytica ... See more keywords
Additions to the checklists of helminth and protozoan parasites of terrestrial mammals and birds in New Zealand
Sign Up to like & getrecommendations! Published in 2018 at "New Zealand Journal of Zoology"
DOI: 10.1080/03014223.2018.1450767
Abstract: ABSTRACT A combined list of additions to previously published checklists of helminth and protozoan parasites of terrestrial mammals and birds in New Zealand is provided. These additions include a total of 21 new host parasite… read more here.
Keywords: protozoan; new zealand; helminth protozoan; birds new ... See more keywords
846 Neospora caninum – an immunotherapeutic protozoan against solid cancers
Sign Up to like & getrecommendations! Published in 2020 at "Journal for ImmunoTherapy of Cancer"
DOI: 10.1136/jitc-2020-sitc2020.0846
Abstract: Background Immunotherapy induces, provides, and/or reactivates anti-tumor immune responses. Some microorganisms also can initiate response that lyzes infected tumor and/or stimulates systemic immunity. Attenuated viruses or bacteria are well studied as oncotherapeutics, but not protozoa… read more here.
Keywords: protozoan; solid cancers; neospora caninum; cancer ... See more keywords
Melittin as a promising anti-protozoan peptide: current knowledge and future prospects
Sign Up to like & getrecommendations! Published in 2021 at "AMB Express"
DOI: 10.1186/s13568-021-01229-1
Abstract: Protozoan diseases such as malaria, leishmaniasis, Chagas disease, and sleeping sickness still levy a heavy toll on human lives. Deplorably, only few classes of anti-protozoan drugs have thus far been developed. The problem is further… read more here.
Keywords: protozoan; melittin promising; current knowledge; anti protozoan ... See more keywords
Perils and Promises of Pathogenic Protozoan Extracellular Vesicles
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2020.00371
Abstract: Extracellular vesicles (EVs) are membranous structures formed during biological processes in living organisms. For protozoan parasites, secretion of EVs can occur directly from the parasite organellar compartments and through parasite-infected or antigen-stimulated host cells in… read more here.
Keywords: extracellular vesicles; protozoan; perils promises; protozoan extracellular ... See more keywords
Crystal Structure of Inhibitor-Bound Bacterial Oligopeptidase B in the Closed State: Similarity and Difference between Protozoan and Bacterial Enzymes
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032286
Abstract: The crystal structure of bacterial oligopeptidase B from Serratia proteamaculans (SpOpB) in complex with a chloromethyl ketone inhibitor was determined at 2.2 Å resolution. SpOpB was crystallized in a closed (catalytically active) conformation. A single… read more here.
Keywords: structure; inhibitor; bacterial oligopeptidase; crystal structure ... See more keywords