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   Articles with "protruding domain" as a keyword



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Bovine natural antibody IgM inhibits the binding of human norovirus protruding domain to its HBGA receptors

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recommendations! Published in 2022 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.13450

Abstract: Human norovirus (HuNoV) is the primary viral pathogen that causes acute gastroenteritis (AGE) in humans. The protruding (P) domain of HuNoV interacts with cell surface histo‐blood group antigens (HBGAs) to initiate infection. Owing to the… read more here.

Keywords: natural antibody; hbga receptors; protruding domain; domain ... See more keywords
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Complete assignment of Ala, Ile, LeuProS, Met and ValProS methyl groups of the protruding domain from human norovirus GII.4 Saga

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recommendations! Published in 2020 at "Biomolecular Nmr Assignments"

DOI: 10.1007/s12104-020-09932-z

Abstract: Attachment of human noroviruses to histo blood group antigens (HBGAs) is thought to be essential for infection, although how this binding event promotes infection is unknown. Recent studies have shown that 60% of all GII.4… read more here.

Keywords: methyl; complete assignment; human norovirus; gii saga ... See more keywords
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Dynamic rotation of the protruding domain enhances the infectivity of norovirus

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recommendations! Published in 2020 at "PLoS Pathogens"

DOI: 10.1371/journal.ppat.1008619

Abstract: Norovirus is the major cause of epidemic nonbacterial gastroenteritis worldwide. Lack of structural information on infection and replication mechanisms hampers the development of effective vaccines and remedies. Here, using cryo-electron microscopy, we show that the… read more here.

Keywords: domain enhances; protruding domain; enhances infectivity; dynamic rotation ... See more keywords
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Atomic Structure of the Murine Norovirus Protruding Domain and Soluble CD300lf Receptor Complex.

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recommendations! Published in 2018 at "Journal of Virology"

DOI: 10.2210/pdb5or7/pdb

Abstract: Human noroviruses are the leading cause of acute gastroenteritis in humans. Noroviruses also infect animals, such as cows, mice, cats, and dogs. How noroviruses bind and enter host cells is still incompletely understood. Recently, the… read more here.

Keywords: receptor; protruding domain; host; murine norovirus ... See more keywords