Safety and Efficacy of Dual Thrombolytic Therapy With Mutant Prourokinase and Small Bolus Alteplase for Ischemic Stroke: A Randomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2023 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2023.1262
Abstract: Importance Dual thrombolytic treatment with small bolus alteplase and mutant prourokinase has the potential to be a safer and more efficacious treatment for ischemic stroke than alteplase alone because mutant prourokinase is designed to act… read more here.
Keywords: alteplase; mutant prourokinase; group; dual thrombolytic ... See more keywords
A randomized study of prourokinase during primary percutaneous coronary intervention in acute ST‐segment elevation myocardial infarction
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DOI: 10.1111/joic.12461
Abstract: OBJECTIVES To evaluate the efficacy and safety of intracoronary administration of prourokinase via balloon catheter during primary percutaneous coronary interventions (PCI) in patients with acute ST-segment elevation myocardial infarction (STEMI). METHODS Acute STEMI patients underwent… read more here.
Keywords: segment; primary percutaneous; group; prourokinase ... See more keywords
Efficacy and safety of intracoronary prourokinase during percutaneous coronary intervention in treating ST-segment elevation myocardial infarction patients: a randomized, controlled study
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DOI: 10.1186/s12872-020-01584-0
Abstract: Background Prourokinase is a single-chain plasminogen activator presenting with fewer hemorrhagic complications and reduced reocclusion rate compared with the conventional fibrinolytic agents in patients with coronary artery disease. However, prourokinase intracoronary injection during PCI for… read more here.
Keywords: intracoronary prourokinase; control; myocardial infarction; group ... See more keywords
Polylactide-Based Stent Coatings: Biodegradable Polymeric Coatings Capable of Maintaining Sustained Release of the Thrombolytic Enzyme Prourokinase
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DOI: 10.3390/ma12244107
Abstract: The novelty of the study is the development, creation, and investigation of biodegradable polymeric membranes based on polylactide, that are capable of directed release of large molecular weight biomolecules, particularly, prourokinase protein (MW = 46… read more here.
Keywords: biodegradable polymeric; polylactide based; based stent; prourokinase ... See more keywords