Monogenic Obesity Syndromes Provide Insights Into the Hypothalamic Regulation of Appetite and Associated Behaviors
Sign Up to like & getrecommendations! Published in 2022 at "Biological psychiatry"
DOI: 10.1016/j.biopsych.2022.01.018
Abstract: Neuronal circuits within the hypothalamus play a critical role in the homeostatic regulation of body weight. By disrupting the development or function of these circuits, human monogenic disorders cause hyperphagia (increased food intake), neuroendocrine abnormalities,… read more here.
Keywords: syndromes provide; regulation; obesity; monogenic obesity ... See more keywords
Can the emerging field of immunometabolism provide insights into neuroinflammation?
Sign Up to like & getrecommendations! Published in 2020 at "Progress in Neurobiology"
DOI: 10.1016/j.pneurobio.2019.101719
Abstract: In the past few years it has become increasingly clear that an understanding of the interaction between metabolism and immune function can provide an insight into cellular responses to challenges. Significant progress has been made… read more here.
Keywords: emerging field; insights neuroinflammation; provide insights; neuroinflammation ... See more keywords
Ancient bears provide insights into Pleistocene ice age refugia in Southeast Alaska.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular ecology"
DOI: 10.1111/mec.16960
Abstract: During the Late Pleistocene, major parts of North America were periodically covered by ice sheets. However, there are still questions about whether ice-free refugia were present in the Alexander Archipelago along the Southeast (SE) Alaska… read more here.
Keywords: bears provide; pleistocene; ice; ancient bears ... See more keywords
Three novel Pseudomonas phages isolated from composting provide insights into the evolution and diversity of tailed phages
Sign Up to like & getrecommendations! Published in 2017 at "BMC Genomics"
DOI: 10.1186/s12864-017-3729-z
Abstract: BackgroundAmong viruses, bacteriophages are a group of special interest due to their capacity of infecting bacteria that are important for biotechnology and human health. Composting is a microbial-driven process in which complex organic matter is… read more here.
Keywords: provide insights; evolution; diversity; novel pseudomonas ... See more keywords
Measures of Health Provide Insights Into the Coping Strategies of Urban Lizards
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Ecology and Evolution"
DOI: 10.3389/fevo.2018.00128
Abstract: Abstract The rapid rate of urbanization worldwide and its consequences for affected species and ecosystems urgently warrants research and action. Whether animals are effectively coping from urbanization is hotly debated, especially since interpretations are based… read more here.
Keywords: provide insights; coping strategies; urban lizards; measures health ... See more keywords
Neural circuits provide insights into reward and aversion
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neural Circuits"
DOI: 10.3389/fncir.2022.1002485
Abstract: Maladaptive changes in the neural circuits associated with reward and aversion result in some common symptoms, such as drug addiction, anxiety, and depression. Historically, the study of these circuits has been hampered by technical limitations.… read more here.
Keywords: insights reward; aversion; provide insights; neural circuits ... See more keywords
Transcriptome and Metabolome Analyses Provide Insights into the Flavonoid Accumulation in Peels of Citrus reticulata ‘Chachi’
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27196476
Abstract: The quality of Chinese medicinal materials depends on the content of bioactive components, which are affected by the environmental factors of different planting regions. In this research, integrated analysis of the transcriptome and metabolome of… read more here.
Keywords: provide insights; reticulata chachi; metabolome analyses; analyses provide ... See more keywords
Leveraging Physiologically Based Modelling to Provide Insights on the Absorption of Paliperidone Extended-Release Formulation under Fed and Fasting Conditions
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15020629
Abstract: Paliperidone was approved by the US FDA in 2006 as an extended-release (ER) tablet (Invega®) for the once-daily treatment of schizophrenia. This osmotic-controlled release oral delivery system (OROS) offers advantages, such as the prevention of… read more here.
Keywords: fed fasting; provide insights; physiologically based; extended release ... See more keywords