Membrane Dynamics of γ-Secretase Provides a Molecular Basis for β-Amyloid Binding and Processing.
Sign Up to like & getrecommendations! Published in 2017 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.7b00208
Abstract: γ-Secretase produces β-amyloid (Aβ) within its presenilin (PS1) subunit, mutations in which cause Alzheimer's disease, and current therapies thus seek to modulate its activity. While the general structure is known from recent electron microscopy studies,… read more here.
Keywords: membrane dynamics; molecular basis; conformation; provides molecular ... See more keywords
The Piranha Genome Provides Molecular Insight Associated to Its Unique Feeding Behavior
Sign Up to like & getrecommendations! Published in 2019 at "Genome Biology and Evolution"
DOI: 10.1093/gbe/evz139
Abstract: Abstract The piranha enjoys notoriety due to its infamous predatory behavior but much is still not understood about its evolutionary origins and the underlying molecular mechanisms for its unusual feeding biology. We sequenced and assembled… read more here.
Keywords: feeding behavior; genome; provides molecular; piranha genome ... See more keywords