Isolation of an Ecotropic Porcine Endogenous Retrovirus PERV-C from a Yucatan SLAD/D Inbred Miniature Swine
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Virology"
DOI: 10.1128/jvi.00062-23
Abstract: Yucatan SLAD/D haplotype miniature swine are candidates as organ donors for xenotransplantation. A full-length replication-competent PERV-C provirus was characterized. The provirus was chromosomally mapped in the pig genome. In vitro, the virus showed increased infectivity… read more here.
Keywords: full length; miniature swine; provirus; perv ... See more keywords
Single-Cell Imaging Shows That the Transcriptional State of the HIV-1 Provirus and Its Reactivation Potential Depend on the Integration Site
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DOI: 10.1128/mbio.00007-22
Abstract: A longstanding question exists on the impact of the HIV-1 integration site on viral gene expression. This unsolved question has significant implications for the search toward an HIV-1 cure, as eradication strategies set up to… read more here.
Keywords: integration site; hiv; provirus; integration ... See more keywords
CpG Methylation Profiles of HIV-1 Proviral DNA in Individuals on ART
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DOI: 10.3390/v13050799
Abstract: The latent HIV-1 reservoir is comprised of stably integrated and intact proviruses with limited to no viral transcription. It has been proposed that latent infection may be maintained by methylation of pro-viral DNA. Here, for… read more here.
Keywords: methylation; provirus; dna; individuals art ... See more keywords