A BET family protein degrader provokes senolysis by targeting NHEJ and autophagy in senescent cells
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-15719-6
Abstract: Although cellular senescence acts primarily as a tumour suppression mechanism, the accumulation of senescent cells in vivo eventually exerts deleterious side effects through inflammatory/tumour-promoting factor secretion. Thus, the development of new drugs that cause the… read more here.
Keywords: senescent cells; family protein; provokes senolysis; protein degrader ... See more keywords