Long chain arabinoxylans shift the mucosa-associated microbiota in the proximal colon of the simulator of the human intestinal microbial ecosystem (M-SHIME)
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2017.02.004
Abstract: Abstract Prebiotic compounds aim at improving human health by targeting beneficial gut microbes. We used a dynamic in vitro model of the human digestive tract (M-SHIME®) to study the modulatory effects of long-chain arabinoxylans (LC-AX)… read more here.
Keywords: long chain; shime; proximal colon; chain arabinoxylans ... See more keywords
Tonic inhibition of murine proximal colon is due to nitrergic suppression of Ca2+ signaling in interstitial cells of Cajal
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-39729-7
Abstract: Spontaneous excitability and contractions of colonic smooth muscle cells (SMCs) are normally suppressed by inputs from inhibitory motor neurons, a behavior known as tonic inhibition. The post-junctional cell(s) mediating tonic inhibition have not been elucidated.… read more here.
Keywords: suppression ca2; inhibition; tonic inhibition; proximal colon ... See more keywords
Self-expandable metal stent placement for malignant obstruction of the proximal colon using single-balloon enteroscopy
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DOI: 10.1055/a-2026-1118
Abstract: Self-expandable metal stents (SEMSs) are widely used around the world for malignant colonic and extracolonic obstruction; however, malignant obstruction in the proximal colon, and complicated and long-segment stenoses are difficult cases [1, 2]. Several articles… read more here.
Keywords: proximal colon; balloon; balloon enteroscopy; single balloon ... See more keywords
The nigro-vagal modulation of the proximal colon is compromised in a model of environmental Parkinson's Disease
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5733401
Abstract: Parkinson’s Disease (PD) is a prevalent neurodegenerative disease characterized by progressive loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc), which results in tremor, rigidity and bradykinesia. Up to 80% of the PD… read more here.
Keywords: proximal colon; motility; physiology; model ... See more keywords
The substantia nigra modulates proximal colon tone and motility in a vagally-dependent manner in the rat
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5733721
Abstract: Previous studies have shown that a monosynaptic pathway connects the substantia nigra pars compacta (SNpc) to neurons of the dorsal motor nucleus of the vagus (DMV). This monosynaptic pathway modulates the vagal control of gastric… read more here.
Keywords: proximal colon; baseline; tone; motility ... See more keywords
Factors Affecting Proximal Colon Cleansing Based on Bowel Movement Kinetics: A Prospective Observational Study
Sign Up to like & getrecommendations! Published in 2019 at "Gastroenterology Research and Practice"
DOI: 10.1155/2019/7032971
Abstract: Background Previous studies have suggested that relatively poor bowel preparation in the proximal colon, compared to that in the distal colon, could decrease the usefulness of colonoscopy. The aim of this study was to determine… read more here.
Keywords: bowel; defecation time; proximal colon; colon ... See more keywords
Impact of the Second Examination of the Proximal Colon on the Adenoma Detection Rate: A Prospective Randomized Controlled Trial
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Translational Gastroenterology"
DOI: 10.14309/ctg.0000000000000557
Abstract: INTRODUCTION: Interval colorectal cancer identified before the next surveillance colonoscopy was more likely to be located in the proximal colon. This study aimed to determine whether a second examination of the proximal colon could increase… read more here.
Keywords: proximal colon; group; examination proximal; colon ... See more keywords
Smart Capsule for Targeted Proximal Colon Microbiome Sampling.
Sign Up to like & getrecommendations! Published in 2022 at "Acta biomaterialia"
DOI: 10.2139/ssrn.4107038
Abstract: The gastrointestinal (GI) tract, particularly the colon region, holds a highly diverse microbial community that plays an important role in the metabolism, physiology, nutrition, and immune function of the host body. Accumulating evidence has revealed… read more here.
Keywords: proximal colon; microbiota; tract; smart capsule ... See more keywords
Dual Effects: Intrastriatal Injection of α-syn N103/tau N368 Preformed Fibrils Promotes Endogenous α-synuclein Aggregates in the Proximal Colon.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Parkinson's disease"
DOI: 10.3233/jpd-223294
Abstract: BACKGROUND Pathological changes in the brain can affect the gastrointestinal tract, whereas there is less evidence regarding the brain-gut axis. OBJECTIVE To identify whether cerebral endogenous phosphorylated α-synuclein induces gastrointestinal dysfunction via the brain-gut axis,… read more here.
Keywords: proximal colon; preformed fibrils; phosphorylated synuclein; brain ... See more keywords
Effects of functional pasta ingredients on different gut microbiota as revealed by TIM-2 in vitro model of the proximal colon.
Sign Up to like & getrecommendations! Published in 2019 at "Beneficial microbes"
DOI: 10.3920/bm2018.0088
Abstract: Diet-related modulation of gut microbiota and its metabolic activity represents an intriguing research context, particularly in the case of disorders related to imbalances in gut microbial communities. We here explored the effects of Bacillus coagulans… read more here.
Keywords: gut microbiota; proximal colon; model proximal; vitro model ... See more keywords