Accounting for proximal variants improves neoantigen prediction
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DOI: 10.1038/s41588-018-0283-9
Abstract: Recent efforts to design personalized cancer immunotherapies use predicted neoantigens, but most neoantigen prediction strategies do not consider proximal (nearby) variants that alter the peptide sequence and may influence neoantigen binding. We evaluated somatic variants… read more here.
Keywords: proximal variants; accounting proximal; somatic variants; neoantigen prediction ... See more keywords