Sign Up to like & get
recommendations!
1
Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac948
Abstract: Abstract PARP1 mediates poly-ADP-ribosylation of proteins on chromatin in response to different types of DNA lesions. PARP inhibitors are used for the treatment of BRCA1/2-deficient breast, ovarian, and prostate cancer. Loss of DNA replication fork…
read more here.
Keywords:
replication;
proximity proteomics;
stressed replication;
parp1 ... See more keywords
Sign Up to like & get
recommendations!
1
Published in 2022 at "Blood"
DOI: 10.1182/blood.2022017419
Abstract: Key Points • Proximity proteomics and siRNA subscreens in endothelial cells reveal proteins associated with regulated actomyosin expulsion of VWF.• PAK2 and septin hetero-oligomeric complexes are required for actomyosin ring function and effective VWF release.
read more here.
Keywords:
proteomics identifies;
expulsion;
identifies septins;
proximity ... See more keywords
Sign Up to like & get
recommendations!
0
Published in 2019 at "Journal of Cell Science"
DOI: 10.1242/jcs.221606
Abstract: ABSTRACT The junctional complexes that couple cardiomyocytes must transmit the mechanical forces of contraction while maintaining adhesive homeostasis. The adherens junction (AJ) connects the actomyosin networks of neighboring cardiomyocytes and is required for proper heart…
read more here.
Keywords:
interactome primary;
cadherin interactome;
primary cardiomyocytes;
proximity proteomics ... See more keywords