The proximity of the G-quadruplex to hemin impacts the intrinsic DNAzyme activity in mitochondria.
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DOI: 10.1039/d0cc08316j
Abstract: The DNAzyme activity of G-quadruplex/hemin in mitochondria has not been characterized. Herein, we report an unexpected difference in the DNAzyme activity between in vitro assays and in mitochondria. Molecular dynamic simulations illustrate how the interaction… read more here.
Keywords: proximity quadruplex; dnazyme activity; dnazyme; quadruplex hemin ... See more keywords