Proximity Tagging Identifies the Glycan-Mediated Glycoprotein Interactors of Galectin-1 in Muscle Stem Cells.
Sign Up to like & getrecommendations! Published in 2021 at "ACS chemical biology"
DOI: 10.1021/acschembio.1c00313
Abstract: Myogenic differentiation, the irreversible developmental process where precursor myoblast muscle stem cells become contractile myotubes, is heavily regulated by glycosylation and glycan-protein interactions at the cell surface and the extracellular matrix. The glycan-binding protein galectin-1… read more here.
Keywords: proximity tagging; glycan mediated; muscle stem; stem cells ... See more keywords
Target protein identification in live cells and organisms with a non-diffusive proximity tagging system
Sign Up to like & getrecommendations! Published in 2024 at "eLife"
DOI: 10.7554/elife.102667
Abstract: Identifying target proteins for bioactive molecules is essential for understanding their mechanisms, developing improved derivatives, and minimizing off-target effects. Despite advances in target identification (target-ID) technologies, significant challenges remain, impeding drug development. Most target-ID methods… read more here.
Keywords: tagging system; system; diffusive proximity; target ... See more keywords