Lithium alleviates neurotoxic prion peptide-induced synaptic damage and neuronal death partially by the upregulation of nuclear target REST and the restoration of Wnt signaling
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DOI: 10.1016/j.neuropharm.2017.05.021
Abstract: &NA; Prion diseases are a group of infectious neurodegenerative diseases characterized by multiple neuropathological hallmarks, including accumulation of PrPSc, synaptic damage, and neuronal death. We previously reported that the repressor element 1‐silencing transcription factor (REST),… read more here.
Keywords: wnt signaling; prion; lithium; rest ... See more keywords