LAUSR

Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors.

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1 Published in 2018 at "Molecular cell"

DOI: 10.1016/j.molcel.2018.02.022

Abstract: Human nineteen complex (NTC) acts as a multimeric E3 ubiquitin ligase in DNA repair and splicing. The transfer of ubiquitin is mediated by Prp19-a homotetrameric component of NTC whose elongated coiled coils serve as an… read more here.

Keywords: pso4 autoinhibited; ubiquitin ligase; stepwise assembly; ligase ... See more keywords