Prp8 positioning of U5 snRNA is linked to 5' splice site recognition.
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DOI: 10.1261/rna.065458.117
Abstract: Prp8 is an essential protein that regulates spliceosome assembly and conformation during pre-mRNA splicing. Recent cryo-EM structures of the spliceosome model Prp8 as a scaffold for the spliceosome's catalytic U snRNA components. Using a new… read more here.
Keywords: snrna; prp8; splice site; site ... See more keywords