Calcimycin Inhibits Cryptococcus neoformans In Vitro and In Vivo by Targeting the Prp8 Intein Splicing.
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DOI: 10.1021/acsinfecdis.2c00137
Abstract: Drug resistance is a significant concern in the treatment of diseases, including cryptococcosis caused by Cryptococcus neoformans (Cne) and Cryptococcus gattii (Cga). Alternative drug targets are necessary to overcome drug resistance before it attains a… read more here.
Keywords: cne; cmn; prp8 intein; intein splicing ... See more keywords