PRPF8 is important for BRCA1-mediated homologous recombination
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DOI: 10.18632/oncotarget.21555
Abstract: Disruption of RNA splicing causes genome instability, which could contribute to cancer etiology. Furthermore, RNA splicing is an emerging anti-cancer target. Thus, we have evaluated the influence of the spliceosome factor PRPF8 and the splicing… read more here.
Keywords: prpf8 depletion; brca1 mediated; homologous recombination; brca1 ... See more keywords