Common genetic variants in PRRC2A are associated with both neuromyelitis optica spectrum disorder and multiple sclerosis in Han Chinese population
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Neurology"
DOI: 10.1007/s00415-020-10184-z
Abstract: The proline-rich coiled-coil 2A (PRRC2A) gene has been reported to underlie risk of various autoimmune diseases. However, no data reveal the risk susceptibility of PRRC2A to neuromyelitis optica spectrum disorder (NMOSD) and multiple sclerosis (MS)… read more here.
Keywords: prrc2a; susceptibility; aqp4 nmosd; spectrum disorder ... See more keywords
A novel m6A reader Prrc2a controls oligodendroglial specification and myelination
Sign Up to like & getrecommendations! Published in 2018 at "Cell Research"
DOI: 10.1038/s41422-018-0113-8
Abstract: While N6-methyladenosine (m6A), the most abundant internal modification in eukaryotic mRNA, is linked to cell differentiation and tissue development, the biological significance of m6A modification in mammalian glial development remains unknown. Here, we identify a… read more here.
Keywords: prrc2a; novel m6a; m6a reader; m6a ... See more keywords